IRIS
VELLECCO, VALENTINA
 Distribuzione geografica
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Continente #
NA - Nord America 1.281
EU - Europa 1.066
AS - Asia 499
AF - Africa 40
SA - Sud America 2
Continente sconosciuto - Info sul continente non disponibili 1
OC - Oceania 1
Totale 2.890
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Nazione #
US - Stati Uniti d'America 1.257
IT - Italia 684
SG - Singapore 203
CN - Cina 158
NL - Olanda 130
VN - Vietnam 98
IE - Irlanda 67
FI - Finlandia 52
CI - Costa d'Avorio 37
DE - Germania 29
SE - Svezia 29
CA - Canada 24
IN - India 19
GB - Regno Unito 17
UA - Ucraina 17
FR - Francia 14
JP - Giappone 8
HK - Hong Kong 6
ES - Italia 4
RU - Federazione Russa 4
BE - Belgio 3
PK - Pakistan 3
PL - Polonia 3
AT - Austria 2
BG - Bulgaria 2
GR - Grecia 2
ID - Indonesia 2
TR - Turchia 2
AL - Albania 1
AU - Australia 1
CH - Svizzera 1
CL - Cile 1
CZ - Repubblica Ceca 1
EC - Ecuador 1
EU - Europa 1
HU - Ungheria 1
LT - Lituania 1
MA - Marocco 1
PT - Portogallo 1
SC - Seychelles 1
SK - Slovacchia (Repubblica Slovacca) 1
ZA - Sudafrica 1
Totale 2.890
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Città #
Chandler 309
Napoli 166
Singapore 163
Naples 132
Amsterdam 129
Dong Ket 98
Millbury 70
Ashburn 65
Princeton 50
Beijing 48
Nanjing 37
Santa Clara 37
Boston 35
Des Moines 27
Ottawa 23
Jacksonville 22
Rome 19
Lawrence 15
Seattle 14
Shenyang 14
Wilmington 14
Nanchang 12
Milan 10
Hebei 9
Boardman 8
Nocera Inferiore 8
Kronberg 7
Pune 7
Hong Kong 6
Jiaxing 6
Ann Arbor 5
Caserta 5
Changsha 5
Dearborn 5
Dublin 5
Houston 5
Pescara 5
Portici 5
Redwood City 5
Salerno 5
Tianjin 5
Trieste 5
Vallo della Lucania 5
Bologna 4
Indiana 4
Lappeenranta 4
Mugnano di Napoli 4
Piana 4
San Mateo 4
Washington 4
Buffalo 3
Dallas 3
Fairfield 3
Formia 3
Helsinki 3
Leawood 3
London 3
Marano Di Napoli 3
Norwalk 3
Padula 3
Roccarainola 3
San Giorgio 3
Sant'Anastasia 3
Serra 3
Stockholm 3
Torre Del Greco 3
Acquappesa 2
Acworth 2
Angri 2
Arienzo 2
Avellino 2
Azzano San Paolo 2
Bergamo 2
Brussels 2
Capodrise 2
Casavatore 2
Cava De' Tirreni 2
Centro 2
Edinburgh 2
Fisciano 2
Fremont 2
Fucecchio 2
Guangzhou 2
Hangzhou 2
Hyderabad 2
Jakarta 2
Kapolei 2
Kunming 2
Lioni 2
Montecorvino Rovella 2
Munich 2
Málaga 2
New Delhi 2
Nocera Superiore 2
Paris 2
Pomigliano D'arco 2
Poznan 2
San Giorgio A Cremano 2
Sargodha 2
Simi Valley 2
Totale 1.769
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Nome #
1,2,4-Thiadiazolidin-3,5-diones as novel hydrogen sulfide donors 202
The ‘‘Janus face” of the thrombin binding aptamer: Investigating the anticoagulant and antiproliferative properties through straightforward chemical modifications 89
Synthesis, structural behaviors and biological properties of thrombin binding aptamers singly modified with chiral m-nitro-benzene glycidoyl moiety 89
Backbone modified TBA analogues endowed with antiproliferative activity 86
Thrombin binding aptamer analogues containing inversion of polarity sites endowed with antiproliferative and anti-motility properties against Calu-6 cells 73
Haemostatic imbalance following carrageenan-induced rat paw oedema. 72
Outstanding effects on antithrombin activity of modified TBA diastereomers containing an optically pure acyclic nucleotide analogue 72
5-Hydroxymethyl-2′-Deoxyuridine Residues in the Thrombin Binding Aptamer: Investigating Anticoagulant Activity by Making a Tiny Chemical Modification 65
In vivo biological activity of a ApoA-I mimetic peptide. 62
Vascular effects of linagliptin in non-obese diabetic mice are glucose-independent and involve positive modulation of the endothelial nitric oxide synthase (eNOS)/caveolin-1 (CAV-1) pathway. 62
Investigating the role of T7 and T12 residues on biological properties of Thrombin Binding Aptamer: enhancement of anticoagulant activity by a single nucleobase modification 60
Site specific replacements of a single loop nucleoside with a dibenzyl linker may switch the activity of TBA from anticoagulant to antiproliferative 60
Site-specific replacement of the thymine methyl group by fluorine in thrombin binding aptamer significantly improves structural stability and anticoagulant activity 60
Investigating the Role of T7 and T12 Residues on the Biological Properties of Thrombin-Binding Aptamer 57
Synthesis, structural studies and biological properties of new TBA analogues containing an acyclic nucleotide 52
Cystathionine β-synthase-derived hydrogen sulfide is involved in human malignant hyperthermia 52
Theonella swinhoei as a source of anti-inflammatory cyclopeptides 51
Anti-inflammatory and immunomodulatory activity of Mangifera indica L. reveals the modulation of COX-2/mPGES-1 axis and Th17/Treg ratio 51
Vasorelaxant effect of the flavonoid galangin on isolated rat thoracic aorta. 48
Apolipoprotein A-I (ApoA-I) Mimetic Peptide P2a by Restoring CholesterolEsterification Unmasks ApoA-I Anti-Inflammatory Endogenous Activity In Vivo. CO-FIRST AUTHOR 47
CROSS TALK BETWEEN TOLL-LIKE RECEPTOR 4 AND PROTEINASE ACTIVATED RECEPTOR 2 IS INVOLVED IN VASCULAR FUNCTION 47
Basal nitric oxide modulates vascular effects of a peptide activating protease activated receptor 2 46
Structural properties and anticoagulant/cytotoxic activities of heterochiral enantiomeric thrombin binding aptamer (TBA) derivatives 43
Biosynthesis of H2S is impaired in non-obese diabetic (NOD) mice 42
Investigating the properties of TBA variants with twin thrombin binding domains 42
Anomalous Kv 7 channel activity in human malignant hyperthermia syndrome unmasks a key role for H2 S and persulfidation in skeletal muscle. 42
Interleukin-17 (IL-17) triggers systemic inflammation, peripheral vascular dysfunction, and related prothrombotic state in a mouse model of Alzheimer's disease 41
Cross-talk between toll-like receptor 4 (TLR4) and proteinase-activated receptor 2 (PAR(2) ) is involved in vascular function 40
A protective role for proteinase activated receptor 2 in airways of lipopolysaccharide-treated rats 39
Structural and biological studies on new TBA analogues: the role of TBA-quadruplex molecularity in the TBA-thrombin complex 38
Anti-inflammatory cyclopeptides from the marine sponge Theonella swinhoei 38
Specific gender-related difference in biosynthesis and release of H2S in isolated rat aorta. 38
Perthamide C Inhibits eNOS and iNOS Expression and Has Immunomodulating Activity In Vivo 37
CROSS TALK BETWEEN TOLL-LIKE RECEPTOR 4 (TLR4) AND PROTEINASE ACTIVATED RECEPTOR 2 (PAR-2) IS INVOLVED IN VASCULAR FUNCTION 37
Hydrogen sulphide is involevd in testsosterone vascular effect 36
cGMP-dependent protein kinase contributes to hydrogen sulfide-stimulated vasorelaxation. 36
Novel tools for the elucidation of physio-pathological role of H2S 36
Hydrogen sulphide is involved in human malignant hypertermia 36
Pro-apoptotic effect of hydrogen sulphide in human melanoma cell lines: A signal transduction analysis 35
Duchenne's muscular dystrophy involves a defective transsulfuration pathway activity 35
Crucial role of androgen receptor in vascular H2S biosynthesis induced by testosterone. 34
Sphingosine-1-phosphate/Sphingosine Kinase Pathway is Involved in Mouse Airway Hyper-responsiveness 33
Characterization of zofenoprilat as an inducer of functional angiogenesis through increased H2 S availability. 33
Hydrogen sulphide induced-dual vascular effect involves arachidonic acid cascade in rat mesenteric arterial bed 32
The vascular effect of zofenopril, a sulfhydrylated ACE inhibitor, involves L-cys/H2S pathway 32
HYDROGEN SULPHIDE IS AN ENDOGENOUS INHIBITOR OF PHOSPHODIESTERASE ACTIVITY 32
Functional contribution of sphingosine-1-phosphate to airway pathology in cigarette smoke-exposed mice 32
Cardiovascular phenotype of mice lacking 3-mercaptopyruvate sulfurtransferase 32
IL-17-induced inflammation modulates the mPGES-1/PPAR-gamma pathway in monocytes/macrophages 32
Hydrogen sulphide is involved in human Malignant Hypertermia 31
Agonism for the bile acid receptor GPBAR1 reverses liver and vascular damage in a mouse model of steatohepatitis 31
An Apolipoprotein A-I mimetic peptide improves reverse cholesterol transport during inflammation and unmasks Apo A-I anti-inflammatory activity in vivo. 30
Phosphodiesterases S-sulfhydration contributes to human skeletal muscle function 30
Nitric oxide and hydrogen sulfide: the gasotransmitter paradigm of the vascular system. 29
Hydrogen sulfide donor AP123 restores endothelial nitric oxide-dependent vascular function in hyperglycemia via a CREB-dependent pathway 28
Perthamides C and D, two new potent anti-inflammatory cyclopeptides from a Solomon Lithistid sponge Theonella swinhoei 28
Involvement of 3′,5′-cyclic inosine monophosphate in cystathionine γ-lyase-dependent regulation of the vascular tone 28
Hydrogen sulfide is an endogenous inhibitor of phosphodiesterase activity 27
Hydrogen sulphide is involved in testosterone vascular effect 27
Sphingosine-1-phosphate modulates vascular permeability and cell recruitment inacute inflammation in vivo. 27
D-Penicillamine modulates hydrogen sulfide (H2S) pathway through selective inhibition of cystathionine-γ-lyase. 25
Hydrogen sulfide accounts for the peripheral vascular effects of zofenopril independently of ACE inhibition. 24
Solomonamides A and B, new anti-inflammatory peptides from Theonella swinhoei 23
Hydrogen sulfide pathway and skeletal muscle: an introductory review. 21
A reverse translational approach reveals the protective roles of Mangifera indica in inflammatory bowel disease 20
Acetoaminophen potentiates staurosporine-induced death in a human neuroblastoma cell line 20
Properties and Potential Antiproliferative Activity of Thrombin-Binding Aptamer (TBA) Derivatives with One or Two Additional G-Tetrads 20
New biologic (Ab-IPL-IL-17) for IL-17-mediated diseases: identification of the bioactive sequence (nIL-17) for IL-17A/F function 19
Searching for novel hydrogen sulfide donors: The vascular effects of two thiourea derivatives 18
Improving the Biological Properties of Thrombin-Binding Aptamer by Incorporation of 8-Bromo-2′-Deoxyguanosine and 2′-Substituted RNA Analogues 16
The endocrine disruptor vinclozolin causes endothelial injury via eNOS/Nox4/IRE1α signaling 16
Inhibition of nitric oxide-stimulated vasorelaxation by carbon monoxide-releasing molecules. 16
Hydrogen sulfide dysfunction in metabolic syndrome-associated vascular complications involves cGMP regulation through soluble guanylyl cyclase persulfidation 15
Proteinase activated receptor-2 counterbalances the vascular effects of endothelin-1 in fibrotic tight-skin mice 15
Biphasic inflammatory response induced by intra-plantar injection of L-cysteine: Role of CBS-derived H2S and S1P/NO signaling 12
Pre-conceptional paternal diet impacts on offspring testosterone homoeostasis via epigenetic modulation of cyp19a1/aromatase activity 12
N-acetyl-L-cysteine reduces testis ROS in obese fathers but fails in protecting offspring from acquisition of epigenetic traits at cyp19a1 and IGF11/H19 ICR loci 10
PROBING THE EFFECTS OF CHEMICAL MODIFICATIONS ON THROMBIN BINDING APTAMER BIOLOGICAL ACTIVITY. 8
CTH/MPST double ablation results in enhanced vasorelaxation and reduced blood pressure via upregulation of the eNOS/sGC pathway 7
Thrombin-Binding Aptamer (TBA) derivatives with one or two additional G-Tetrads: properties and potential antiproliferative activity 6
Defective Bile Acid Signaling Promotes Vascular Dysfunction, Supporting a Role for G‐Protein Bile Acid Receptor 1/Farnesoid X Receptor Agonism and Statins in the Treatment of Nonalcoholic Fatty Liver Disease 5
Totale 3.130
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Categoria #
all - tutte 13.072
article - articoli 0
book - libri 0
conference - conferenze 0
curatela - curatele 0
other - altro 0
patent - brevetti 0
selected - selezionate 0
volume - volumi 0
Totale 13.072
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Totale Lug Ago Sett Ott Nov Dic Gen Feb Mar Apr Mag Giu
2019/2020143 0 0 0 0 24 7 12 18 10 27 34 11
2020/2021368 18 10 14 4 30 49 16 14 62 7 33 111
2021/2022454 4 5 6 5 5 15 3 27 81 33 103 167
2022/2023778 69 69 18 85 71 82 3 80 127 132 25 17
2023/2024471 18 69 60 35 25 53 10 75 4 14 74 34
2024/2025331 90 107 21 66 47 0 0 0 0 0 0 0
Totale 3.130