IRIS
PERISSUTTI, ELISA
 Distribuzione geografica
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Continente #
NA - Nord America 5.400
AS - Asia 5.306
EU - Europa 4.772
SA - Sud America 667
Continente sconosciuto - Info sul continente non disponibili 266
AF - Africa 183
OC - Oceania 7
Totale 16.601
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Nazione #
US - Stati Uniti d'America 5.148
SG - Singapore 2.299
RU - Federazione Russa 1.809
IT - Italia 1.107
CN - Cina 1.050
VN - Vietnam 1.005
BR - Brasile 520
DE - Germania 466
HK - Hong Kong 366
FR - Francia 331
NL - Olanda 192
FI - Finlandia 180
UA - Ucraina 154
CA - Canada 140
IE - Irlanda 139
GB - Regno Unito 130
IN - India 99
JP - Giappone 82
BD - Bangladesh 81
SE - Svezia 55
MX - Messico 50
AR - Argentina 49
CI - Costa d'Avorio 48
ES - Italia 44
ZA - Sudafrica 44
PL - Polonia 43
KR - Corea 33
PH - Filippine 33
GR - Grecia 29
IQ - Iraq 29
PK - Pakistan 29
TR - Turchia 28
EC - Ecuador 27
MA - Marocco 27
ID - Indonesia 25
TH - Thailandia 25
CO - Colombia 19
AT - Austria 17
VE - Venezuela 16
IR - Iran 15
BG - Bulgaria 13
JM - Giamaica 13
TW - Taiwan 13
JO - Giordania 12
LT - Lituania 12
PY - Paraguay 12
TN - Tunisia 12
CL - Cile 11
SA - Arabia Saudita 10
EG - Egitto 9
IL - Israele 9
UZ - Uzbekistan 9
LB - Libano 7
NI - Nicaragua 7
SN - Senegal 7
UY - Uruguay 7
BE - Belgio 6
DZ - Algeria 6
HN - Honduras 6
KZ - Kazakistan 6
MY - Malesia 6
TT - Trinidad e Tobago 6
AE - Emirati Arabi Uniti 5
AU - Australia 5
CH - Svizzera 5
CR - Costa Rica 5
CZ - Repubblica Ceca 5
ET - Etiopia 5
KE - Kenya 5
SK - Slovacchia (Repubblica Slovacca) 5
SV - El Salvador 5
AL - Albania 4
AM - Armenia 4
AZ - Azerbaigian 4
EE - Estonia 4
EU - Europa 4
PR - Porto Rico 4
PS - Palestinian Territory 4
SY - Repubblica araba siriana 4
AO - Angola 3
BO - Bolivia 3
DM - Dominica 3
GE - Georgia 3
GT - Guatemala 3
HU - Ungheria 3
NP - Nepal 3
SI - Slovenia 3
BA - Bosnia-Erzegovina 2
BS - Bahamas 2
BW - Botswana 2
BZ - Belize 2
CM - Camerun 2
GA - Gabon 2
HR - Croazia 2
KG - Kirghizistan 2
KW - Kuwait 2
LV - Lettonia 2
MD - Moldavia 2
NO - Norvegia 2
PA - Panama 2
Totale 16.309
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Città #
Singapore 1.087
San Jose 956
Moscow 433
Naples 370
Chandler 368
Beijing 355
Hong Kong 346
Ashburn 315
Ho Chi Minh City 265
Santa Clara 252
Hanoi 222
Council Bluffs 178
Jacksonville 159
Amsterdam 157
The Dalles 130
Lauterbourg 117
Los Angeles 112
Hefei 109
Millbury 105
Princeton 97
Napoli 88
Nanjing 81
Menlo Park 76
Woodbridge 75
New York 74
Munich 69
Houston 68
São Paulo 65
Tokyo 64
Buffalo 63
Boston 53
Dallas 51
Redondo Beach 51
Krefeld 50
Frankfurt am Main 48
Ottawa 47
Haiphong 44
Wilmington 44
Des Moines 43
Phoenix 40
Helsinki 39
Da Nang 37
Turku 32
Brooklyn 31
Orem 30
Falkenstein 29
Mexico City 29
Dong Ket 28
Toronto 27
Warsaw 27
Nanchang 25
Atlanta 24
Bad Bellingen 24
Chicago 24
Milan 24
Rome 24
Ann Arbor 22
Johannesburg 20
Montreal 20
Casablanca 19
Hebei 19
Lawrence 19
London 19
Nuremberg 19
Norwalk 18
San Giorgio a Cremano 18
Seoul 18
Thessaloniki 18
Tianjin 18
Chennai 17
Hải Dương 17
Pozzuoli 16
Redwood City 16
Manchester 15
Rio de Janeiro 15
Seattle 15
Stockholm 15
Denver 14
Dublin 14
Lahore 14
Can Tho 13
Dearborn 13
Jiaxing 13
Biên Hòa 12
Changsha 12
Salerno 12
San Francisco 12
Shenyang 12
Augusta 11
Bexley 11
Dhaka 11
Falls Church 11
Indiana 11
Mugnano di Napoli 11
Amman 10
Baghdad 10
Bangkok 10
Cambridge 10
Sofia 10
Vienna 10
Totale 8.421
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Nome #
1,2,4-Thiadiazolidin-3,5-diones as novel hydrogen sulfide donors 366
Design, Synthesis and Biological Evaluation of Novel N-Arylpiperazines Containing a 4,5-Dihydrothiazole Ring 304
Development of 1,2,3-Triazole-Based Sphingosine Kinase Inhibitors and Their Evaluation as Antiproliferative Agents 216
Chemical Composition of PM10 at Urban Sites in Naples (Italy) 194
Synthesis of phenylpyrimidinones as guanylyl cyclase C inhibitors 187
MONTELUKAST ESTERS AND PHARMACEUTICAL COMPOSITIONS CONTAINING THE SAME 178
Design of Sphingosine Kinases Inhibitors: Challenges and Recent Developments 176
Identification of a pepducin acting as S1P3 receptor antagonist 173
HYBRIDS BETWEEN H2S-DONORS AND BETAMETHASONE 17-VALERATE OR TRIAMCINOLONE ACETONIDE: IN VITRO EFFECT IN ASTHMA TREATMENT 173
Antagonizing S1P3 receptor with cell-penetrating pepducins in skeletal muscle fibrosis 171
Heavy Metals Size Distribution in PM10 and Environmental-Sanitary Risk Analysis in Acerra (Italy) 169
The Role of 5-HT1A Receptor in the Cancer as a New Opportunity in Medicinal Chemistry 166
A New Process for the Synthesis of Budesonide 21-Phosphate and Evaluation in a Murine Model of Inflammation 165
Synthesis and in Vitro Screening of New Series of 2,6-Dipeptidyl-anthraquinones: Influence of Side Chain Length on HIV-1 Nucleocapsid Inhibitors 164
Synthesis, in vitro and in vivo pharmacological evaluation of serotoninergic ligands containing an isonicotinic nucleus 162
Synthesis, docking studies, and pharmacological evaluation of 5HT 2C ligands containing the N′-cyanoisonicotinamidine or N′-cyanopicolinamidine nucleus 162
Isothiocyanate-Corticosteroid Conjugates against asthma: Unity makes strength 158
New 5-HT1A, 5HT2Aand 5HT2Creceptor ligands containing a picolinic nucleus: Synthesis, in vitro and in vivo pharmacological evaluation 158
Synthesis and Pharmacological Screening of Pyridopyrimidines as Effective Anti-Diarrheal Agents through the Suppression of Cyclic Nucleotide Accumulation 157
Synthesis, Chiral Resolution and Enantiomers Absolute Configuration of 4-Nitropropranolol and 7-Nitropropranolol 156
A convenient synthesis by microwave irradiation of an active metabolite (EXP-3174) of losartan. 155
Synthesis of Arylpiperazine Derivatives as Protease Activated Receptor 1 Antagonists and Their Evaluation as Antiproliferative Agents 155
Non-Natural Linker Configuration in 2,6-Dipeptidyl-Anthraquinones Enhances the Inhibition of TAR RNA Binding/Annealing Activities by HIV-1 NC and Tat Proteins 154
Development validation of LC-MS/MS method and determination of pharmacokinetic parameters of the stroke neuroprotectant neurounina-1 in beagle dog plasma after intravenous administration 151
Level, potential sources of polycyclic aromatic hydrocarbons (PAHs) in particulate matter (PM10) in Naples 149
Hybrids between H2S-donors and betamethasone 17-valerate or triamcinolone acetonide inhibit mast cell degranulation and promote hyperpolarization of bronchial smooth muscle cells 149
Synthesis, Biological Evaluation and Docking Studies of PAR2-AP Derived Pseudopeptides as Inhibitors of Kallikrein 5 and 6 148
PCB levels in adipose tissue of dogs from illegal dumping sites in Campania region (Italy) 147
New Potent 5-HT2A Receptor Ligands Containing a N'-Cyanopicolinamidine Nucleus: Synthesis and In Vitro Pharmacological Evaluation 146
5‑HT1A Receptor: An Old Target as a New Attractive Tool in Drug Discovery from Central Nervous System to Cancer 146
Prednisone-hydrogen sulfide releasing hybrid shows improved therapeutic profile in asthma 145
Design, synthesis and biological evaluation of TAR and cTAR binders as HIV-​1 nucleocapsid inhibitors 145
3-Nitroatenolol: First Synthesis, Chiral Resolution and Enantiomers’ Absolute Configuration 144
Newly Synthesized Indolylacetic Derivatives Reduce Tumor Necrosis Factor-Mediated Neuroinflammation and Prolong Survival in Amyotrophic Lateral Sclerosis Mice 144
Synthesis and Binding Affinities for 5-HT1A, 5-HT2A and 5-HT2C receptors of a series of 1- and 2-(4-arylpiperazinylalkyl)-4-(benzoyl)-1,2,3-triazole derivatives. 142
Synthesis and antinociceptive Activity of Peptides Related to Interleukin-1b193-195 Lys-Pro-Thr. 140
Synthesis and In Vitro Pharmacological Evaluation of Novel 2-Hydroxypropyl-4-arylpiperazine Derivatives as Serotoninergic Ligands 140
Microwave Assisted Organic Synthesis of Heterocycles in Aqueous Media: Recent Advances in Medicinal Chemistry 140
Pharmacokinetics of Dihydroergocristine and its major metabolite 8'-Hydroxy-Dihydroergocristine in Human plasma 139
Synthesis and in vitro activities of NK-1 antagonists derived from L-Triptophan. 139
New Serotoninergic Ligands Containing Indolic and Methyl Indolic Nuclei: Synthesis and In Vitro Pharmacological Evaluation 138
Phenol derived CVFM analogs inhibitors of ras farnesyl transferase possessing cellular in vitro activity. 136
Synthesis, biological activity and conformational study of 1,4-benzoxazine dderivatives as potassium channel modulators. 136
A convenient strategy of dimerization by microwave heating and using 2,5-diketopiperazine as scaffold. 136
Arylpiperazine Derivatives and Cancer: A New Challenge in Medicinal Chemistry 135
Synthesis, Docking Studies and Pharmacological Evaluation of Serotoninergic Ligands Containing a 5-Norbornene-2-Carboxamide Nucleus 135
Synthesis, Pharmacological Evaluation, and Molecular Modeling Studies of Novel Peptidic CAAX Analogues as Farnesyl-Protein-Transferase Inhibitors 133
Combined Use of Factorial Design and Comparative Molecular Field Analysis (CoMFA): a Case Study. 132
Conformation-activity relationship of peptide T and new pseudocyclic hexapeptide analogs. 131
Synthesis of benzamide derivatives and their evaluation as antiprion agents 131
H2s donors and their use in medicinal chemistry 131
Design, Synthesis and Evaluation of Novel Molecular Hybrids between Antiglaucoma Drugs and H2S Donors 130
Synthesis and Biological Activity of Benzotriazole Derivatives Structurally Related to Trazodone. 130
le microonde nella sintesi organica. fondamenti e applicazioni in chimica farmaceutica 129
BUDESONIDE 21-PHOSPHATE SALTS AND PHARMACEUTICAL COMPOSITIONS CONTAINING THE SAME 129
Trends in h2s-donors chemistry and their effects in cardiovascular diseases 129
Budesonide 21-phosphate sodium salt for use as anti-inflammatory or anti-asthmatic agent. 128
Quantification of dapaconazole in human plasma using high-​performance liquid chromatography coupled to tandem mass spectrometry: Application to a phase I study 128
Synthesis by microwave irradiation of a substituted benzoxazine parallel library with preferential relaxant activity for guinea pig trachealis 126
Racemic synthesis and solid phase peptide synthesis application of the chimeric Valine/Leucine derivative 2-amino-3,3,4-trimethyl-pentanoic acid 125
Structure-activity relationships study of isothiocyanates for H2S releasing properties: 3-Pyridyl-isothiocyanate as a new promising cardioprotective agent 125
Synthesis of 1-naphthylpiperazine derivatives as serotoninergic ligands and their evaluation as antiproliferative agents. 124
Synthesis, Local Anesthetic Activity and QSAR Studies for a Set of N-[2-(alkylamino)-ethyl]benzotriazol-X-yl Acetamides. 124
Synthesis, Biological Activity and Conformational Study of 1,4-Benzoxazine Derivatives as Potassium Channel Modulators 123
Fragment-based de novo design of a cystathionine γ-lyase selective inhibitor blocking hydrogen sulfide production 122
A valuable synthesis of reduced peptide bond by microwave irradiation 120
Synthesis of Nα-Fmoc N,N′-bis-Boc-5-, 6- and 8-guanyl-1,2,3,4-tetrahydroisoquinoline-3-carboxylic Acid (5-GTIC, 6-GTIC and 8-GTIC) 118
Synthesis and vasorelaxant activity of new 1,4-benzoxazine derivatives potassium channel openers. 118
Synthesis and Structure-Activity Relationships of Antiinflammatory 1-Methyl-2-(4-X-benzoyl)imidazole-5-acetic Acids. 117
Identification of a novel selective CSE inhibitor through a combined pharmacological and metabolomic approach 117
Synthesis, docking studies, and pharmacological evaluation of 2-hydroxypropyl-4-arylpiperazine derivatives as serotoninergic ligands 116
Synthesis of new 1,2,3-benzotriazin-4-one-arylpiperazine derivatives as 5-HT1A serotonin receptor ligands. 115
Synthesis and Antiinflammatory-Analgesic Profile of 1-Methyl-2-(4-X-benzoyl)imidazole-5-carboxylic Acids. 115
A convenient synthesis by microwave heating and pharmacological evaluation of novel benzoyltriazole and saccharine derivatives as 5-HT1A receptor ligands. 114
Synthesis of substituted benzamides as anti-inflammatory agents that inhibit preferentially cyclooxygenase 1 but do not cause gastric damage. 114
Kallikrein Protease Activated Receptor (PAR) Axis: An Attractive Target for Drug Development 114
New 5-Hydroxytryptamine1A Receptor Ligands Containing a Norbornene Nucleus: Synthesis and in Vitro Pharmacological Evaluation 113
Microwave Solvent Free Regioselective 1,3 Dipolar Cycloaddition in the Synthesis of 1,4 Substituted [1,2,3]-Triazoles as Amide Bond Isosteres 112
Synthesis by microwave irradiation and binding properties of novel 5-HT1A receptor ligands. 112
Propylthiouracil quantification in human plasma by high-​performance liquid chromatography coupled with electrospray tandem mass spectrometry: Application in a bioequivalence study 112
H2S donating corticosteroids: Design, synthesis and biological evaluation in a murine model of asthma 111
Synthesis and structure-activity of antisense peptides corresponding to the region for CaM-binding domain of the inducible nitric oxide synthase 109
The application of microwave irradiation as new convenient synthetic procedure in drug discovery 108
Minimal structural requirements for agonist activity of PAR-2 activating peptides. 108
A suitable 1,2,4-oxadiazoles synthesis by microwave irradiation 107
Preparation and local anesthetic activity of benzotriazinone and benzoyltriazole derivatives. 106
Probing the shape of a hydrophobic pocket in the active site of delta-opioid antagonists 105
Pills of Multi-Target H2S Donating Molecules for Complex Diseases 105
Comparative bioavailability of two losartan formulations in healthy human volunteers after a single dose administration. 104
Synthesis and biological activity of tripeptide FR113680 analogues containing unconventional amino acids. 104
Efficient Microwave Combinatorial Parallel and Non Parallel Synthesis of N-Alkylated Glycine Methyl Esters as Peptide Building Blocks 103
Structure-Affinity Relationship Studies on Benzotriazole Derivatives Binding to 5-HT Receptor Subtypes. 102
Microwave-enhanced solution coupling of the a,a-dialkyl amino acid, Aib 101
Synthesis and biological activity of pseudopeptides inhibitors of Ras farnesyl transferase containing unconventional amino acids. 101
Synthesis of 6-beta-D-glucosyl and 6-nitroxy (-)-galanthamine derivatives as acetylcholinesterase inhibitors 100
Human Tissue Kallikrein S1 Subsite Recognition of Non-Natural Basic Amino Acids 99
Synthesis of 2-Methyl-3-indolylacetic Derivatives as Anti-Inflammatory Agents That Inhibit Preferentially Cyclooxygenase 1 without Gastric Damage 99
Conformational analysis of three NK1 tripeptide antagonists: A proton nuclear magnetic resonance study 98
Montelukast salts and pharmaceutical compositions containing the same 98
New Insights into the Structure-Activity Relationship and Neuroprotective Profile of Benzodiazepinone Derivatives of Neurounina-1 as Modulators of the Na+/Ca2+Exchanger Isoforms 98
Totale 13.712
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Categoria #
all - tutte 56.580
article - articoli 0
book - libri 0
conference - conferenze 0
curatela - curatele 0
other - altro 0
patent - brevetti 0
selected - selezionate 0
volume - volumi 0
Totale 56.580
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Totale Lug Ago Sett Ott Nov Dic Gen Feb Mar Apr Mag Giu
2021/2022875 0 0 7 146 15 52 3 37 126 84 162 243
2022/2023924 138 112 19 89 73 83 15 62 120 139 52 22
2023/2024902 33 107 183 21 25 20 41 72 204 22 123 51
2024/20254.064 194 216 56 82 74 255 393 288 262 460 1.461 323
2025/20267.362 806 462 833 620 1.241 270 837 388 1.052 498 214 141
2026/2027601 157 259 185 0 0 0 0 0 0 0 0 0
Totale 16.601