IRIS
SUMMA, Vincenzo
 Distribuzione geografica
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Continente #
AS - Asia 5.565
NA - Nord America 3.625
EU - Europa 3.311
SA - Sud America 607
AF - Africa 100
OC - Oceania 3
Continente sconosciuto - Info sul continente non disponibili 1
Totale 13.212
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Nazione #
US - Stati Uniti d'America 3.502
SG - Singapore 2.757
RU - Federazione Russa 1.484
IT - Italia 1.025
VN - Vietnam 907
CN - Cina 879
BR - Brasile 482
HK - Hong Kong 457
FR - Francia 250
DE - Germania 155
JP - Giappone 125
GB - Regno Unito 91
IN - India 91
NL - Olanda 72
KR - Corea 65
CA - Canada 62
AR - Argentina 48
BD - Bangladesh 45
FI - Finlandia 39
SE - Svezia 37
MX - Messico 36
PH - Filippine 33
TH - Thailandia 33
ZA - Sudafrica 31
TW - Taiwan 25
AT - Austria 21
ID - Indonesia 21
CI - Costa d'Avorio 20
IQ - Iraq 19
PL - Polonia 19
IE - Irlanda 17
PK - Pakistan 17
BE - Belgio 16
CH - Svizzera 16
EC - Ecuador 16
TR - Turchia 16
ES - Italia 15
UA - Ucraina 15
CO - Colombia 14
VE - Venezuela 13
PY - Paraguay 10
AE - Emirati Arabi Uniti 8
CL - Cile 8
SA - Arabia Saudita 8
TN - Tunisia 8
BO - Bolivia 7
EG - Egitto 6
IL - Israele 6
JO - Giordania 6
LB - Libano 6
MA - Marocco 6
PE - Perù 6
UZ - Uzbekistan 6
KE - Kenya 5
KZ - Kazakistan 5
LT - Lituania 5
CR - Costa Rica 4
ET - Etiopia 4
IR - Iran 4
PA - Panama 4
RS - Serbia 4
AO - Angola 3
AZ - Azerbaigian 3
GE - Georgia 3
GR - Grecia 3
JM - Giamaica 3
NG - Nigeria 3
OM - Oman 3
PS - Palestinian Territory 3
PT - Portogallo 3
SI - Slovenia 3
SY - Repubblica araba siriana 3
UY - Uruguay 3
AM - Armenia 2
AU - Australia 2
BG - Bulgaria 2
DK - Danimarca 2
DZ - Algeria 2
GM - Gambi 2
HR - Croazia 2
IS - Islanda 2
KG - Kirghizistan 2
LV - Lettonia 2
MU - Mauritius 2
MY - Malesia 2
NO - Norvegia 2
NP - Nepal 2
PR - Porto Rico 2
RO - Romania 2
TT - Trinidad e Tobago 2
AL - Albania 1
BA - Bosnia-Erzegovina 1
BB - Barbados 1
BH - Bahrain 1
BY - Bielorussia 1
CG - Congo 1
CU - Cuba 1
DO - Repubblica Dominicana 1
EE - Estonia 1
EU - Europa 1
Totale 13.192
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Città #
Singapore 1.239
San Jose 623
Hong Kong 442
Moscow 382
Ashburn 310
Santa Clara 309
Naples 294
Ho Chi Minh City 266
Hefei 260
Beijing 233
Hanoi 195
Millbury 193
Chandler 182
Lauterbourg 150
The Dalles 148
Lawrence 139
Tokyo 111
Los Angeles 96
Des Moines 95
Redondo Beach 72
Rome 71
Buffalo 55
Dallas 52
Seoul 51
São Paulo 51
Milan 43
New York 42
Wilmington 41
Haiphong 39
Da Nang 37
Düsseldorf 34
Munich 32
Amsterdam 31
Ottawa 29
Frankfurt am Main 28
London 27
Chicago 25
Orem 23
Seattle 21
Helsinki 20
Mexico City 19
Council Bluffs 17
Brooklyn 16
Brussels 16
Fairfield 16
Napoli 16
Sant'Arpino 16
Bangkok 15
Warsaw 15
Hải Dương 14
Johannesburg 14
Atlanta 13
Bologna 13
Nuremberg 13
Belo Horizonte 12
Bến Tre 12
Curitiba 12
Montreal 12
Rio de Janeiro 12
Can Tho 11
Chennai 11
Scafati 11
Guangzhou 10
Houston 10
Thái Nguyên 10
Vienna 10
Boston 9
Denver 9
Falkenstein 9
Lappeenranta 9
Lucca 9
Manchester 9
Nanjing 9
San Giorgio a Cremano 9
Stockholm 9
Turku 9
Arezzo 8
Augusta 8
Brasília 8
Dublin 8
Mumbai 8
Palermo 8
San Francisco 8
Toronto 8
Biên Hòa 7
Cape Town 7
Dearborn 7
Greenville 7
Long Xuyen 7
Portsmouth 7
Quito 7
Shenzhen 7
Siena 7
Asunción 6
Betim 6
Bắc Ninh 6
Campinas 6
Dhaka 6
Jeddah 6
New Delhi 6
Totale 7.096
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Nome #
6-Bromoindirubin-3′-oxime intercepts GSK3 signaling to promote and enhance skeletal muscle differentiation affecting miR-206 expression in mice 218
Broad-spectrum coronavirus 3C-like protease peptidomimetic inhibitors effectively block SARS-CoV-2 replication in cells: Design, synthesis, biological evaluation, and X-ray structure determination 170
Anti-inflammatory and immunomodulatory activity of Mangifera indica L. reveals the modulation of COX-2/mPGES-1 axis and Th17/Treg ratio 170
Phytochemical investigation and antioxidant properties of unripe tomato cultivars (Solanum lycopersicum L.) 161
Tackling triple negative breast cancer with HDAC inhibitors: 6 is the isoform! 157
Continuous-Flow Technology for Chemical Rearrangements: A Powerful Tool to Generate Pharmaceutically Relevant Compounds 150
Nutraceutical formulation based on a synergic combination of melatonin and palmitoylethanolamide for the management of allergic events 141
Characterization and quantification of intact glucosinolates in Catozza rapeseeds: A promising food matrix for nutraceuticals development as a source of hydrogen sulfide 138
Agri-Food Waste Recycling for Healthy Remedies: Biomedical Potential of Nutraceuticals from Unripe Tomatoes (Solanum lycopersicum L.) 134
Visible-light photocatalytic functionalization of isocyanides for the synthesis of secondary amides and ketene aminals 134
Optimization of Phlorizin Extraction from Annurca Apple Tree Leaves Using Response Surface Methodology 131
Rejuvenating the [1, 2, 3]-triazolo [1,5-a]quinoxalin-4(5H)-one scaffold: Synthesis and derivatization in a sustainable guise and preliminary antimicrobial evaluation 130
Effects of Food-Derived Antioxidant Compounds on In Vitro Heavy Metal Intestinal Bioaccessibility 130
3-​Hydroxy-​4-​oxo-​4H-​pyrido[1,​2-​a]​pyrimidine-​2-​carboxylates; fast access to a heterocyclic scaffold for HIV-​1 integrase inhibitors 129
SARS-CoV-2 Entry Inhibitors: Small Molecules and Peptides Targeting Virus or Host Cells 128
3-​Hydroxy-​4-​oxo-​4H-​pyrido[1,​2-​a]​pyrimidine-​2-​carboxylates-​A new class of HIV-​1 integrase inhibitors 127
Chasing a Breath of Fresh Air in Cystic Fibrosis (CF): Therapeutic Potential of Selective HDAC6 Inhibitors to Tackle Multiple Pathways in CF Pathophysiology 125
Unveiling the modulation of Pseudomonas aeruginosa virulence and biofilm formation by selective histone deacetylase 6 inhibitors 124
Photo-Flow Technology for Chemical Rearrangements: A Powerful Tool to Generate Pharmaceutically Relevant Compounds 124
Optimization of Ursolic Acid Extraction in Oil from Annurca Apple to Obtain Oleolytes with Potential Cosmeceutical Application 123
Beneficial Contribution to Glucose Homeostasis by an Agro-Food Waste Product Rich in Abscisic Acid: Results from a Randomized Controlled Trial 123
Chiral Azole Derivatives. 2. Synthesis of Enantiomerically Pure 1-​Alkylimidazoles 121
Validation of an LC-MS/MS Method for the Determination of Abscisic Acid Concentration in a Real-World Setting 120
Thinned Nectarines, an Agro-Food Waste with Antidiabetic Potential: HPLC-HESI-MS/MS Phenolic Characterization and In Vitro Evaluation of Their Beneficial Activities 120
Researches on antiviral agents. 4. Studies on the chemistry of 6-​methyl-​2-​methoxy-​4-​O-​acyloxy and 6-​methyl-​2,​4-​di-​O-​acyloxypyrimidine derivatives as new acylation reagents and inhibitors of uracil DNA glycosylases 119
4,​5-​Dihydroxypyrimidine Carboxamides and N-​Alkyl-​5-​hydroxypyrimidinone Carboxamides Are Potent, Selective HIV Integrase Inhibitors with Good Pharmacokinetic Profiles in Preclinical Species 118
Advances in the development of macrocyclic inhibitors of hepatitis C virus NS3-​4A protease 118
Application of a Rapid and Simple Technological Process to Increase Levels and Bioccessibility of Free Phenolic Compounds in Annurca Apple Nutraceutical Product 114
Dihydroxy-​pyrimidine and N-​methylpyrimidone HIV-​integrase inhibitors: Improving cell based activity by the quaternization of a chiral center 113
MK-5172, a selective inhibitor of hepatitis C virus NS3/4a protease with broad activity across genotypes and resistant variants 113
Natural Chalcones for the Management of Obesity Disease 110
Nirmatrelvir treatment of SARS-CoV-2-infected mice blunts antiviral adaptive immune responses 110
Efficacy of selective histone deacetylase 6 inhibition in mouse models of Pseudomonas aeruginosa infection: A new glimpse for reducing inflammation and infection in cystic fibrosis 110
A Food-Grade Method for Enhancing the Levels of Low Molecular Weight Proanthocyanidins with Potentially High Intestinal Bioavailability 110
Inhibitors of the Hepatitis C Virus NS3 Protease with Basic Amine Functionality at the P3-​Amino Acid N-​Terminus: Discovery and Optimization of a New Series of P2-​P4 Macrocycles 110
Evaluation of HIV-​1 integrase inhibitors on human primary macrophages using a luciferase-​based single-​cycle phenotypic assay 109
The monoethyl ester of meconic acid is an active site inhibitor of HCV NS5B RNA-​dependent RNA polymerase 109
Binding of a Noncovalent Inhibitor Exploiting the S' region Stabilizes the Hepatitis C virus NS3 Protease Conformation in the Absence of Cofactor 109
Routes to HIV-​integrase inhibitors: efficient synthesis of bicyclic pyrimidones by ring expansion or amination at a benzylic position 109
Preparation of arylaminocarbonyl pyrrolo-​fused tricyclic sulfonamides as inhibitors of hepatitis B virus 109
Inhibitors of hepatitis C virus NS3​/4A: α-​Ketoamide based macrocyclic inhibitors 108
Structural characterization of the Hepatitis C Virus NS3 protease from genotype 3a: The basis of the genotype 1b vs. 3a inhibitor potency shift 107
Phosphorous acid analogs of novel P2-​P4 macrocycles as inhibitors of HCV-​NS3 protease 106
Easy access to α-ketoamides as SARS-CoV-2 and MERS Mpro inhibitors via the PADAM oxidation route 105
Structure-​Based Identification of HIV-​1 Nucleocapsid Protein Inhibitors Active against Wild-​Type and Drug-​Resistant HIV-​1 Strains 105
Development of potent macrocyclic inhibitors of genotype 3a HCV NS3​/4A protease 105
Methyl-Transferase-Like Protein 16 (METTL16): The Intriguing Journey of a Key Epitranscriptomic Player Becoming an Emerging Biological Target 104
Early metabolic response to acute myocardial ischaemia in patients undergoing elective coronary angioplasty 104
Optimization and Validation of Procyanidins Extraction and Phytochemical Profiling of Seven Herbal Matrices of Nutraceutical Interest 102
Targeting SARS-CoV-2 Proteases and Polymerase for COVID-19 Treatment: State of the Art and Future Opportunities 101
Synthesis and antiviral properties of novel 7-​heterocyclic substituted 7-​deaza-​adenine nucleoside inhibitors of Hepatitis C NS5B polymerase 96
5,6-Dihydroxypyrimidine Scaffold to Target HIV-1 Nucleocapsid Protein 92
Cytopathic SARS-CoV-2 screening on VERO-E6 cells in a large-scale repurposing effort 91
Bicyclic pyrimidones as inhibitors of HIV-​integrase 87
Combined Peptide and Small-Molecule Approach toward Nonacidic THIQ Inhibitors of the KEAP1/NRF2 Interaction 84
A Rapid and Reliable Spectrofluorimetric Method to Measure the Urinary Lactulose/Mannitol Ratio for Dysbiosis Assessment 82
Synthesis and SAR of 2-​(4,​5-​dihydroxy-​6-​carboxy-​pyrimidinyl) thiophenes as inhibitors of the Hepatitis C Virus NS5B Polymerase 81
Antiviral agents for the treatment of hepatitis C virus infections 79
Antiretroviral activity, pharmacokinetics, and tolerability of MK-0518, a novel inhibitor of HIV-1 integrase, dosed as monotherapy for 10 days in treatment-naive HIV-1-infected individuals 79
A Focus on Severe Acute Respiratory Syndrome ( SARS ) Coronavirus ( SARS‐CoVs ) 1 and 2 79
Preparation of heteroaryl heptanamide derivatives for use in the treatment of parasitic diseases 78
The metabolism and disposition of a potent inhibitor of hepatitis C virus NS3​/4A protease 78
Thiol-Reactive or Redox-Active: Revising a Repurposing Screen Led to a New Invalidation Pipeline and Identified a True Noncovalent Inhibitor Against Papain-like Protease from SARS-CoV-2 77
Heterocyclic compounds used in the treatment of kinetoplastid infection and their preparation 77
Preparation of macrocyclic quinoxaline peptide as HCV NS3 protease inhibitor 73
Discovery and Antiviral Profile of New Sulfamoylbenzamide Derivatives as HBV Capsid Assembly Modulators 72
Studies of metabolism and disposition of potent human immunodeficiency virus (HIV) integrase inhibitors using 19F-​NMR spectroscopy 72
Preparation of arylaminocarbonyl bicyclic sulfonamides as inhibitors of hepatitis B virus 72
Preparation of arylaminocarbonyl bicyclic sulfonamides as inhibitors of hepatitis B virus 72
4-​Hydroxy-​5-​pyrrolinone-​3-​carboxamide HIV-​1 integrase inhibitors 70
Natural Compounds Inhibit SARS-CoV-2 nsp13 Unwinding and ATPase Enzyme Activities 70
From dihydroxypyrimidine carboxylic acids to carboxamide HIV integrase inhibitors 69
Approaching a new era for hepatitis C virus therapy: inhibitors of the NS3-​4A serine protease and the NS5B RNA-​dependent RNA polymerase 69
Development of macrocyclic inhibitors of HCV NS3​/4A protease with cyclic constrained P2-​P4 linkers 68
Allosteric inhibitors of hepatitis C virus NS5B polymerase thumb domain site II: Structure-​based design and synthesis of new templates 68
Discovery of a selective series of inhibitors of Plasmodium falciparum HDACs 68
Discovery, synthesis and optimization of a new series of selective HIV integrase inhibitors leading to MK-​0518 currently in Phase III clinical trial for treatment of HIV​/AIDS 68
Management of chronic myeloid leukaemia patients treated with ponatinib in a real-life setting: A retrospective analysis from the monitoring registries of the Italian Medicines Agency (AIFA) 67
Synthesis of aryl 2-​benzofuranyl- and 2-​indolyl(aryl)​carbinols of high enantiomeric purity via palladium-​catalyzed heteroannulation of chiral arylpropargylic alcohols 67
A useful methodology for the regioselective deprotection of 1,​3-​dibenzyluracils 67
Dermatological and​/or cosmetic peptides for use in skin treatment 67
Application of an in Vitro Blood-Brain Barrier Model in the Selection of Experimental Drug Candidates for the Treatment of Huntington's Disease 67
Preparation of hydroxyoxopyridopyrimidinecarboxamides as HIV integrase inhibitors 66
Compositions useful for the treatment of viral diseases 66
Preparation of dihydroxypyridinylpyrimidinecarboxamide derivatives for use as HIV-​1 nucleocapsid inhibitors 65
VX-​950 vertex​/mitsubishi 65
Hiv integrase inhibitors 65
Identification of Inhibitors of SARS-CoV-2 3CL-Pro Enzymatic Activity Using a Small Molecule in Vitro Repurposing Screen 65
Discovery of α,​γ-​Diketo Acids as Potent Selective and Reversible Inhibitors of Hepatitis C Virus NS5b RNA-​Dependent RNA Polymerase 64
Preparation of macrocyclic quinoline and naphthyridine peptides as HCV NS3 protease inhibitors useful in the treatment of hepatitis C infection 64
Inhibitors of the hepatitis C virus NS3 protease with basic amine functionality at the P3-amino acid N-terminus: Discovery and optimization of a new series of P2-P4 macrocycles 63
Identification of Isoform 2 Acid-Sensing Ion Channel Inhibitors as Tool Compounds for Target Validation Studies in CNS 63
Preparation of macrocyclic peptides as HCV NS3 protease inhibitors 63
Heterocyclic compounds useful in the treatment of disorders that are ameliorated by inhibition of HDAC 63
A preparation of tetrahydro-​4H-​pyrido[1,​2-​a]​pyrimidine derivatives, useful as HIV integrase inhibitors 63
Preparation of N-​Ph dicarbamate derivatives as HIV reverse transcriptase inhibitors 63
Design, Synthesis, and Biological Evaluation of New 1-(Aryl-1 H-pyrrolyl)(phenyl)methyl-1 H-imidazole Derivatives as Antiprotozoal Agents 62
Prdm16-mediated H3K9 methylation controls fibro-adipogenic progenitors identity during skeletal muscle repair 62
Improved Selective Class i HDAC and Novel Selective HDAC3 Inhibitors: Beyond Hydroxamic Acids and Benzamides 61
Aryl propargylic alcohols of high enantiomeric purity via lipase catalyzed resolutions 61
Totale 9.715
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Categoria #
all - tutte 41.728
article - articoli 0
book - libri 0
conference - conferenze 0
curatela - curatele 0
other - altro 0
patent - brevetti 0
selected - selezionate 0
volume - volumi 0
Totale 41.728
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Totale Lug Ago Sett Ott Nov Dic Gen Feb Mar Apr Mag Giu
2020/202161 0 0 0 0 0 0 0 0 0 0 32 29
2021/2022570 8 4 7 31 16 18 0 36 22 26 88 314
2022/2023657 143 39 10 53 56 49 57 66 112 17 41 14
2023/2024663 47 67 110 69 27 18 21 47 14 25 147 71
2024/20254.198 194 343 34 88 145 190 388 292 504 417 1.213 390
2025/20266.881 866 575 670 630 1.014 179 741 513 1.033 449 211 0
Totale 13.439