IRIS
SUMMA, Vincenzo
 Distribuzione geografica
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Continente #
AS - Asia 5.640
NA - Nord America 4.072
EU - Europa 3.435
SA - Sud America 624
Continente sconosciuto - Info sul continente non disponibili 230
AF - Africa 103
OC - Oceania 3
Totale 14.107
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Nazione #
US - Stati Uniti d'America 3.915
SG - Singapore 2.759
RU - Federazione Russa 1.484
IT - Italia 1.123
VN - Vietnam 907
CN - Cina 887
BR - Brasile 495
HK - Hong Kong 458
FR - Francia 255
DE - Germania 155
JP - Giappone 125
BD - Bangladesh 102
GB - Regno Unito 93
IN - India 92
CA - Canada 80
NL - Olanda 79
KR - Corea 65
AR - Argentina 48
FI - Finlandia 39
MX - Messico 39
SE - Svezia 37
PH - Filippine 34
TH - Thailandia 33
ZA - Sudafrica 31
TW - Taiwan 25
AT - Austria 21
ID - Indonesia 21
CH - Svizzera 20
CI - Costa d'Avorio 20
IQ - Iraq 19
PL - Polonia 19
ES - Italia 18
IE - Irlanda 18
PK - Pakistan 17
BE - Belgio 16
EC - Ecuador 16
TR - Turchia 16
UA - Ucraina 15
CO - Colombia 14
VE - Venezuela 14
CL - Cile 10
PY - Paraguay 10
AE - Emirati Arabi Uniti 9
SA - Arabia Saudita 8
TN - Tunisia 8
BO - Bolivia 7
CR - Costa Rica 7
PE - Perù 7
EG - Egitto 6
IL - Israele 6
JM - Giamaica 6
JO - Giordania 6
LB - Libano 6
LT - Lituania 6
MA - Marocco 6
UZ - Uzbekistan 6
KE - Kenya 5
KZ - Kazakistan 5
ET - Etiopia 4
IR - Iran 4
MY - Malesia 4
NP - Nepal 4
PA - Panama 4
RO - Romania 4
RS - Serbia 4
AO - Angola 3
AZ - Azerbaigian 3
BG - Bulgaria 3
GE - Georgia 3
GR - Grecia 3
NG - Nigeria 3
OM - Oman 3
PS - Palestinian Territory 3
PT - Portogallo 3
SC - Seychelles 3
SI - Slovenia 3
SV - El Salvador 3
SY - Repubblica araba siriana 3
TT - Trinidad e Tobago 3
UY - Uruguay 3
AM - Armenia 2
AU - Australia 2
BB - Barbados 2
DK - Danimarca 2
DZ - Algeria 2
GM - Gambi 2
HN - Honduras 2
HR - Croazia 2
IS - Islanda 2
KG - Kirghizistan 2
LV - Lettonia 2
MU - Mauritius 2
NO - Norvegia 2
PR - Porto Rico 2
AL - Albania 1
BA - Bosnia-Erzegovina 1
BH - Bahrain 1
BY - Bielorussia 1
CG - Congo 1
CU - Cuba 1
Totale 13.855
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Città #
Singapore 1.240
San Jose 635
Hong Kong 442
Ashburn 400
Moscow 382
Naples 326
Santa Clara 317
Ho Chi Minh City 266
Hefei 260
Beijing 233
Hanoi 195
Millbury 193
Chandler 182
Lauterbourg 150
The Dalles 148
Lawrence 139
Tokyo 111
Los Angeles 110
Des Moines 95
Redondo Beach 72
Rome 72
Dallas 68
Buffalo 64
São Paulo 60
New York 52
Seoul 51
Milan 50
Wilmington 41
Haiphong 39
Da Nang 37
Düsseldorf 34
Munich 32
Amsterdam 31
Ottawa 29
Frankfurt am Main 28
London 28
Chicago 27
Orem 27
Memphis 25
Mexico City 21
Seattle 21
Helsinki 20
Council Bluffs 18
Atlanta 17
Brooklyn 17
Houston 17
Brussels 16
Fairfield 16
Montreal 16
Napoli 16
Sant'Arpino 16
Bangkok 15
Warsaw 15
Denver 14
Hải Dương 14
Johannesburg 14
San Francisco 14
Bologna 13
Nuremberg 13
Toronto 13
Belo Horizonte 12
Bến Tre 12
Curitiba 12
Rio de Janeiro 12
Can Tho 11
Chennai 11
Scafati 11
Boston 10
Guangzhou 10
Thái Nguyên 10
Vienna 10
Dublin 9
Falkenstein 9
Lappeenranta 9
Lucca 9
Manchester 9
Nanjing 9
Palermo 9
Phoenix 9
San Giorgio a Cremano 9
Stockholm 9
Turku 9
Arezzo 8
Augusta 8
Brasília 8
Florence 8
Mumbai 8
Philadelphia 8
Biên Hòa 7
Cape Town 7
Dearborn 7
Dhaka 7
Greenville 7
Long Xuyen 7
New Delhi 7
Portsmouth 7
Quito 7
Salerno 7
Shenzhen 7
Siena 7
Totale 7.379
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Nome #
6-Bromoindirubin-3′-oxime intercepts GSK3 signaling to promote and enhance skeletal muscle differentiation affecting miR-206 expression in mice 218
Agri-Food Waste Recycling for Healthy Remedies: Biomedical Potential of Nutraceuticals from Unripe Tomatoes (Solanum lycopersicum L.) 196
Anti-inflammatory and immunomodulatory activity of Mangifera indica L. reveals the modulation of COX-2/mPGES-1 axis and Th17/Treg ratio 178
Broad-spectrum coronavirus 3C-like protease peptidomimetic inhibitors effectively block SARS-CoV-2 replication in cells: Design, synthesis, biological evaluation, and X-ray structure determination 176
Tackling triple negative breast cancer with HDAC inhibitors: 6 is the isoform! 169
Phytochemical investigation and antioxidant properties of unripe tomato cultivars (Solanum lycopersicum L.) 166
Continuous-Flow Technology for Chemical Rearrangements: A Powerful Tool to Generate Pharmaceutically Relevant Compounds 154
Nutraceutical formulation based on a synergic combination of melatonin and palmitoylethanolamide for the management of allergic events 144
Effects of Food-Derived Antioxidant Compounds on In Vitro Heavy Metal Intestinal Bioaccessibility 141
Characterization and quantification of intact glucosinolates in Catozza rapeseeds: A promising food matrix for nutraceuticals development as a source of hydrogen sulfide 140
Unveiling the modulation of Pseudomonas aeruginosa virulence and biofilm formation by selective histone deacetylase 6 inhibitors 137
Optimization of Phlorizin Extraction from Annurca Apple Tree Leaves Using Response Surface Methodology 136
Beneficial Contribution to Glucose Homeostasis by an Agro-Food Waste Product Rich in Abscisic Acid: Results from a Randomized Controlled Trial 136
Rejuvenating the [1, 2, 3]-triazolo [1,5-a]quinoxalin-4(5H)-one scaffold: Synthesis and derivatization in a sustainable guise and preliminary antimicrobial evaluation 135
Visible-light photocatalytic functionalization of isocyanides for the synthesis of secondary amides and ketene aminals 135
Photo-Flow Technology for Chemical Rearrangements: A Powerful Tool to Generate Pharmaceutically Relevant Compounds 132
3-​Hydroxy-​4-​oxo-​4H-​pyrido[1,​2-​a]​pyrimidine-​2-​carboxylates; fast access to a heterocyclic scaffold for HIV-​1 integrase inhibitors 132
3-​Hydroxy-​4-​oxo-​4H-​pyrido[1,​2-​a]​pyrimidine-​2-​carboxylates-​A new class of HIV-​1 integrase inhibitors 129
SARS-CoV-2 Entry Inhibitors: Small Molecules and Peptides Targeting Virus or Host Cells 129
Validation of an LC-MS/MS Method for the Determination of Abscisic Acid Concentration in a Real-World Setting 128
Chasing a Breath of Fresh Air in Cystic Fibrosis (CF): Therapeutic Potential of Selective HDAC6 Inhibitors to Tackle Multiple Pathways in CF Pathophysiology 128
Optimization of Ursolic Acid Extraction in Oil from Annurca Apple to Obtain Oleolytes with Potential Cosmeceutical Application 127
Chiral Azole Derivatives. 2. Synthesis of Enantiomerically Pure 1-​Alkylimidazoles 124
Application of a Rapid and Simple Technological Process to Increase Levels and Bioccessibility of Free Phenolic Compounds in Annurca Apple Nutraceutical Product 123
Thinned Nectarines, an Agro-Food Waste with Antidiabetic Potential: HPLC-HESI-MS/MS Phenolic Characterization and In Vitro Evaluation of Their Beneficial Activities 122
4,​5-​Dihydroxypyrimidine Carboxamides and N-​Alkyl-​5-​hydroxypyrimidinone Carboxamides Are Potent, Selective HIV Integrase Inhibitors with Good Pharmacokinetic Profiles in Preclinical Species 121
Researches on antiviral agents. 4. Studies on the chemistry of 6-​methyl-​2-​methoxy-​4-​O-​acyloxy and 6-​methyl-​2,​4-​di-​O-​acyloxypyrimidine derivatives as new acylation reagents and inhibitors of uracil DNA glycosylases 121
Advances in the development of macrocyclic inhibitors of hepatitis C virus NS3-​4A protease 120
Efficacy of selective histone deacetylase 6 inhibition in mouse models of Pseudomonas aeruginosa infection: A new glimpse for reducing inflammation and infection in cystic fibrosis 115
Dihydroxy-​pyrimidine and N-​methylpyrimidone HIV-​integrase inhibitors: Improving cell based activity by the quaternization of a chiral center 115
MK-5172, a selective inhibitor of hepatitis C virus NS3/4a protease with broad activity across genotypes and resistant variants 114
A Food-Grade Method for Enhancing the Levels of Low Molecular Weight Proanthocyanidins with Potentially High Intestinal Bioavailability 113
Evaluation of HIV-​1 integrase inhibitors on human primary macrophages using a luciferase-​based single-​cycle phenotypic assay 112
Routes to HIV-​integrase inhibitors: efficient synthesis of bicyclic pyrimidones by ring expansion or amination at a benzylic position 112
Natural Chalcones for the Management of Obesity Disease 111
Nirmatrelvir treatment of SARS-CoV-2-infected mice blunts antiviral adaptive immune responses 111
The monoethyl ester of meconic acid is an active site inhibitor of HCV NS5B RNA-​dependent RNA polymerase 110
Binding of a Noncovalent Inhibitor Exploiting the S' region Stabilizes the Hepatitis C virus NS3 Protease Conformation in the Absence of Cofactor 110
Inhibitors of the Hepatitis C Virus NS3 Protease with Basic Amine Functionality at the P3-​Amino Acid N-​Terminus: Discovery and Optimization of a New Series of P2-​P4 Macrocycles 110
Preparation of arylaminocarbonyl pyrrolo-​fused tricyclic sulfonamides as inhibitors of hepatitis B virus 110
Inhibitors of hepatitis C virus NS3​/4A: α-​Ketoamide based macrocyclic inhibitors 109
Structural characterization of the Hepatitis C Virus NS3 protease from genotype 3a: The basis of the genotype 1b vs. 3a inhibitor potency shift 109
Phosphorous acid analogs of novel P2-​P4 macrocycles as inhibitors of HCV-​NS3 protease 107
Development of potent macrocyclic inhibitors of genotype 3a HCV NS3​/4A protease 107
Methyl-Transferase-Like Protein 16 (METTL16): The Intriguing Journey of a Key Epitranscriptomic Player Becoming an Emerging Biological Target 106
Structure-​Based Identification of HIV-​1 Nucleocapsid Protein Inhibitors Active against Wild-​Type and Drug-​Resistant HIV-​1 Strains 106
Early metabolic response to acute myocardial ischaemia in patients undergoing elective coronary angioplasty 106
Easy access to α-ketoamides as SARS-CoV-2 and MERS Mpro inhibitors via the PADAM oxidation route 105
Optimization and Validation of Procyanidins Extraction and Phytochemical Profiling of Seven Herbal Matrices of Nutraceutical Interest 103
Targeting SARS-CoV-2 Proteases and Polymerase for COVID-19 Treatment: State of the Art and Future Opportunities 102
Synthesis and antiviral properties of novel 7-​heterocyclic substituted 7-​deaza-​adenine nucleoside inhibitors of Hepatitis C NS5B polymerase 97
5,6-Dihydroxypyrimidine Scaffold to Target HIV-1 Nucleocapsid Protein 97
A Rapid and Reliable Spectrofluorimetric Method to Measure the Urinary Lactulose/Mannitol Ratio for Dysbiosis Assessment 94
Cytopathic SARS-CoV-2 screening on VERO-E6 cells in a large-scale repurposing effort 91
Bicyclic pyrimidones as inhibitors of HIV-​integrase 88
Combined Peptide and Small-Molecule Approach toward Nonacidic THIQ Inhibitors of the KEAP1/NRF2 Interaction 86
Antiviral agents for the treatment of hepatitis C virus infections 84
Synthesis and SAR of 2-​(4,​5-​dihydroxy-​6-​carboxy-​pyrimidinyl) thiophenes as inhibitors of the Hepatitis C Virus NS5B Polymerase 82
Thiol-Reactive or Redox-Active: Revising a Repurposing Screen Led to a New Invalidation Pipeline and Identified a True Noncovalent Inhibitor Against Papain-like Protease from SARS-CoV-2 81
Preparation of heteroaryl heptanamide derivatives for use in the treatment of parasitic diseases 80
Antiretroviral activity, pharmacokinetics, and tolerability of MK-0518, a novel inhibitor of HIV-1 integrase, dosed as monotherapy for 10 days in treatment-naive HIV-1-infected individuals 80
A Focus on Severe Acute Respiratory Syndrome ( SARS ) Coronavirus ( SARS‐CoVs ) 1 and 2 80
The metabolism and disposition of a potent inhibitor of hepatitis C virus NS3​/4A protease 79
Heterocyclic compounds used in the treatment of kinetoplastid infection and their preparation 79
Preparation of macrocyclic quinoxaline peptide as HCV NS3 protease inhibitor 76
Preparation of arylaminocarbonyl bicyclic sulfonamides as inhibitors of hepatitis B virus 75
Discovery, synthesis and optimization of a new series of selective HIV integrase inhibitors leading to MK-​0518 currently in Phase III clinical trial for treatment of HIV​/AIDS 74
Preparation of arylaminocarbonyl bicyclic sulfonamides as inhibitors of hepatitis B virus 74
Discovery and Antiviral Profile of New Sulfamoylbenzamide Derivatives as HBV Capsid Assembly Modulators 73
From dihydroxypyrimidine carboxylic acids to carboxamide HIV integrase inhibitors 73
Studies of metabolism and disposition of potent human immunodeficiency virus (HIV) integrase inhibitors using 19F-​NMR spectroscopy 73
Allosteric inhibitors of hepatitis C virus NS5B polymerase thumb domain site II: Structure-​based design and synthesis of new templates 72
Development of macrocyclic inhibitors of HCV NS3​/4A protease with cyclic constrained P2-​P4 linkers 71
Approaching a new era for hepatitis C virus therapy: inhibitors of the NS3-​4A serine protease and the NS5B RNA-​dependent RNA polymerase 71
4-​Hydroxy-​5-​pyrrolinone-​3-​carboxamide HIV-​1 integrase inhibitors 71
Natural Compounds Inhibit SARS-CoV-2 nsp13 Unwinding and ATPase Enzyme Activities 71
Discovery of a selective series of inhibitors of Plasmodium falciparum HDACs 70
Dermatological and​/or cosmetic peptides for use in skin treatment 70
Discovery of α,​γ-​Diketo Acids as Potent Selective and Reversible Inhibitors of Hepatitis C Virus NS5b RNA-​Dependent RNA Polymerase 69
Synthesis of aryl 2-​benzofuranyl- and 2-​indolyl(aryl)​carbinols of high enantiomeric purity via palladium-​catalyzed heteroannulation of chiral arylpropargylic alcohols 69
Preparation of hydroxyoxopyridopyrimidinecarboxamides as HIV integrase inhibitors 69
A useful methodology for the regioselective deprotection of 1,​3-​dibenzyluracils 68
Preparation of N-​Ph dicarbamate derivatives as HIV reverse transcriptase inhibitors 68
Application of an in Vitro Blood-Brain Barrier Model in the Selection of Experimental Drug Candidates for the Treatment of Huntington's Disease 68
Identification and in vitro characterization of a new series of potent and highly selective G9a inhibitors as novel anti-fibroadipogenic agents 68
Management of chronic myeloid leukaemia patients treated with ponatinib in a real-life setting: A retrospective analysis from the monitoring registries of the Italian Medicines Agency (AIFA) 67
VX-​950 vertex​/mitsubishi 67
Compositions useful for the treatment of viral diseases 67
Identification of Isoform 2 Acid-Sensing Ion Channel Inhibitors as Tool Compounds for Target Validation Studies in CNS 66
Preparation of dihydroxypyridinylpyrimidinecarboxamide derivatives for use as HIV-​1 nucleocapsid inhibitors 66
Aryl propargylic alcohols of high enantiomeric purity via lipase catalyzed resolutions 66
Preparation of macrocyclic quinoline and naphthyridine peptides as HCV NS3 protease inhibitors useful in the treatment of hepatitis C infection 66
Hiv integrase inhibitors 66
Inhibitors of the hepatitis C virus NS3 protease with basic amine functionality at the P3-amino acid N-terminus: Discovery and optimization of a new series of P2-P4 macrocycles 65
Discovery and synthesis of HIV integrase inhibitors: Dihydroxypyrimidine-​4-​carboxamides as novel potent and selective agents 65
Heterocyclic compounds useful in the treatment of disorders that are ameliorated by inhibition of HDAC 65
Prdm16-mediated H3K9 methylation controls fibro-adipogenic progenitors identity during skeletal muscle repair 65
Identification of Inhibitors of SARS-CoV-2 3CL-Pro Enzymatic Activity Using a Small Molecule in Vitro Repurposing Screen 65
Preparation of macrocyclic peptides as HCV NS3 protease inhibitors 64
Preparation of macrocyclic peptides as HCV NS3 protease inhibitors 64
Totale 10.075
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Categoria #
all - tutte 45.225
article - articoli 0
book - libri 0
conference - conferenze 0
curatela - curatele 0
other - altro 0
patent - brevetti 0
selected - selezionate 0
volume - volumi 0
Totale 45.225
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Totale Lug Ago Sett Ott Nov Dic Gen Feb Mar Apr Mag Giu
2021/2022570 8 4 7 31 16 18 0 36 22 26 88 314
2022/2023657 143 39 10 53 56 49 57 66 112 17 41 14
2023/2024663 47 67 110 69 27 18 21 47 14 25 147 71
2024/20254.198 194 343 34 88 145 190 388 292 504 417 1.213 390
2025/20267.266 866 575 670 630 1.014 179 741 513 1.033 449 248 348
2026/2027283 283 0 0 0 0 0 0 0 0 0 0 0
Totale 14.107