IRIS
SUMMA, Vincenzo
 Distribuzione geografica
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Continente #
NA - Nord America 1.609
EU - Europa 858
AS - Asia 646
AF - Africa 18
SA - Sud America 5
Continente sconosciuto - Info sul continente non disponibili 1
Totale 3.137
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Nazione #
US - Stati Uniti d'America 1.578
IT - Italia 636
SG - Singapore 483
CN - Cina 102
IN - India 38
NL - Olanda 33
DE - Germania 32
CA - Canada 31
SE - Svezia 31
FR - Francia 25
RU - Federazione Russa 24
CI - Costa d'Avorio 18
GB - Regno Unito 15
BE - Belgio 14
IE - Irlanda 13
FI - Finlandia 12
CH - Svizzera 7
UA - Ucraina 7
VN - Vietnam 5
IR - Iran 4
BR - Brasile 3
JP - Giappone 3
RS - Serbia 3
TW - Taiwan 3
CL - Cile 2
GR - Grecia 2
AE - Emirati Arabi Uniti 1
AM - Armenia 1
BD - Bangladesh 1
ES - Italia 1
EU - Europa 1
HK - Hong Kong 1
IL - Israele 1
IQ - Iraq 1
KG - Kirghizistan 1
KZ - Kazakistan 1
LT - Lituania 1
PL - Polonia 1
SI - Slovenia 1
Totale 3.137
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Città #
Singapore 396
Santa Clara 292
Millbury 193
Chandler 181
Naples 155
Lawrence 139
Des Moines 94
Ashburn 57
Beijing 55
Rome 42
Wilmington 38
Ottawa 29
Milan 25
Amsterdam 21
Napoli 16
Sant'Arpino 16
Fairfield 15
Brussels 14
Bologna 10
Scafati 10
Arezzo 8
Palermo 8
Augusta 7
Dearborn 7
Helsinki 7
Shenzhen 7
Siena 7
Greenville 6
Guangzhou 6
Redwood City 6
Ahmedabad 5
Bonn 5
Gurgaon 5
Kronberg 5
Rimini 5
Salerno 5
Woodbridge 5
Afragola 4
Bacoli 4
Baronissi 4
Braunschweig 4
Cava De' Tirreni 4
Dong Ket 4
Dublin 4
Enfield 4
Hangzhou 4
Irpin 4
Lappeenranta 4
London 4
Maastricht 4
Mondolfo 4
Portici 4
Pune 4
San Mateo 4
Wohlen 4
Ardabil 3
Boston 3
Delhi 3
Fribourg 3
Jalandhar 3
Leawood 3
Maniago 3
Messina 3
Moscow 3
Mugnano di Napoli 3
Nanjing 3
Nocera Superiore 3
Norwalk 3
Offanengo 3
Palagano 3
Redmond 3
Sarno 3
Seattle 3
Shaoxing 3
Stockholm 3
Torre Annunziata 3
Acquappesa 2
Albano Laziale 2
Ann Arbor 2
Belo Horizonte 2
Campobasso 2
Catanzaro 2
Chengdu 2
Chennai 2
Coimbatore 2
Concorezzo 2
Dallas 2
Desio 2
Emeryville 2
Ercolano 2
Hayes 2
Kizuki-sumiyoshicho 2
Kunming 2
Limatola 2
Matera 2
Mohali 2
Mumbai 2
New Taipei City 2
Noida 2
Nola 2
Totale 2.085
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Nome #
6-Bromoindirubin-3′-oxime intercepts GSK3 signaling to promote and enhance skeletal muscle differentiation affecting miR-206 expression in mice 78
Anti-inflammatory and immunomodulatory activity of Mangifera indica L. reveals the modulation of COX-2/mPGES-1 axis and Th17/Treg ratio 54
Preparation of arylaminocarbonyl pyrrolo-​fused tricyclic sulfonamides as inhibitors of hepatitis B virus 52
5,6-Dihydroxypyrimidine Scaffold to Target HIV-1 Nucleocapsid Protein 50
Targeting SARS-CoV-2 Proteases and Polymerase for COVID-19 Treatment: State of the Art and Future Opportunities 49
A Focus on Severe Acute Respiratory Syndrome ( SARS ) Coronavirus ( SARS‐CoVs ) 1 and 2 47
Phytochemical investigation and antioxidant properties of unripe tomato cultivars (Solanum lycopersicum L.) 45
Bicyclic pyrimidones as inhibitors of HIV-​integrase 44
Visible-light photocatalytic functionalization of isocyanides for the synthesis of secondary amides and ketene aminals 42
Easy access to α-ketoamides as SARS-CoV-2 and MERS Mpro inhibitors via the PADAM oxidation route 41
Continuous-Flow Technology for Chemical Rearrangements: A Powerful Tool to Generate Pharmaceutically Relevant Compounds 39
3-​Hydroxy-​4-​oxo-​4H-​pyrido[1,​2-​a]​pyrimidine-​2-​carboxylates-​A new class of HIV-​1 integrase inhibitors 39
SARS-CoV-2 Entry Inhibitors: Small Molecules and Peptides Targeting Virus or Host Cells 39
Broad-spectrum coronavirus 3C-like protease peptidomimetic inhibitors effectively block SARS-CoV-2 replication in cells: Design, synthesis, biological evaluation, and X-ray structure determination 38
3-​Hydroxy-​4-​oxo-​4H-​pyrido[1,​2-​a]​pyrimidine-​2-​carboxylates; fast access to a heterocyclic scaffold for HIV-​1 integrase inhibitors 37
Chasing a Breath of Fresh Air in Cystic Fibrosis (CF): Therapeutic Potential of Selective HDAC6 Inhibitors to Tackle Multiple Pathways in CF Pathophysiology 36
Synthesis and SAR of 2-​(4,​5-​dihydroxy-​6-​carboxy-​pyrimidinyl) thiophenes as inhibitors of the Hepatitis C Virus NS5B Polymerase 35
Thinned Nectarines, an Agro-Food Waste with Antidiabetic Potential: HPLC-HESI-MS/MS Phenolic Characterization and In Vitro Evaluation of Their Beneficial Activities 35
Antiviral agents for the treatment of hepatitis C virus infections 34
4,​5-​Dihydroxypyrimidine Carboxamides and N-​Alkyl-​5-​hydroxypyrimidinone Carboxamides Are Potent, Selective HIV Integrase Inhibitors with Good Pharmacokinetic Profiles in Preclinical Species 33
Chiral Azole Derivatives. 2. Synthesis of Enantiomerically Pure 1-​Alkylimidazoles 33
Rejuvenating the [1, 2, 3]-triazolo [1,5-a]quinoxalin-4(5H)-one scaffold: Synthesis and derivatization in a sustainable guise and preliminary antimicrobial evaluation 32
Natural Compounds Inhibit SARS-CoV-2 nsp13 Unwinding and ATPase Enzyme Activities 32
4-​Hydroxy-​5-​pyrrolinone-​3-​carboxamide HIV-​1 integrase inhibitors 31
Photo-Flow Technology for Chemical Rearrangements: A Powerful Tool to Generate Pharmaceutically Relevant Compounds 30
Efficacy of selective histone deacetylase 6 inhibition in mouse models of Pseudomonas aeruginosa infection: A new glimpse for reducing inflammation and infection in cystic fibrosis 30
Heterocyclic compounds used in the treatment of kinetoplastid infection and their preparation 30
Preparation of arylaminocarbonyl bicyclic sulfonamides as inhibitors of hepatitis B virus 30
Antiretroviral activity, pharmacokinetics, and tolerability of MK-0518, a novel inhibitor of HIV-1 integrase, dosed as monotherapy for 10 days in treatment-naive HIV-1-infected individuals 29
Combined Peptide and Small-Molecule Approach toward Nonacidic THIQ Inhibitors of the KEAP1/NRF2 Interaction 28
Tackling triple negative breast cancer with HDAC inhibitors: 6 is the isoform! 27
Preparation of heteroaryl heptanamide derivatives for use in the treatment of parasitic diseases 26
Allosteric inhibitors of hepatitis C virus NS5B polymerase thumb domain site II: Structure-​based design and synthesis of new templates 26
Advances in the development of macrocyclic inhibitors of hepatitis C virus NS3-​4A protease 26
Preparation of arylaminocarbonyl bicyclic sulfonamides as inhibitors of hepatitis B virus 26
Application of a Rapid and Simple Technological Process to Increase Levels and Bioccessibility of Free Phenolic Compounds in Annurca Apple Nutraceutical Product 26
Improved Selective Class i HDAC and Novel Selective HDAC3 Inhibitors: Beyond Hydroxamic Acids and Benzamides 25
Preparation of dihydroxypyridinylpyrimidinecarboxamide derivatives for use as HIV-​1 nucleocapsid inhibitors 25
Aryl propargylic alcohols of high enantiomeric purity via lipase catalyzed resolutions 25
Binding of a Noncovalent Inhibitor Exploiting the S' region Stabilizes the Hepatitis C virus NS3 Protease Conformation in the Absence of Cofactor 25
Application of an in Vitro Blood-Brain Barrier Model in the Selection of Experimental Drug Candidates for the Treatment of Huntington's Disease 25
Discovery and Antiviral Profile of New Sulfamoylbenzamide Derivatives as HBV Capsid Assembly Modulators 24
Cytopathic SARS-CoV-2 screening on VERO-E6 cells in a large-scale repurposing effort 24
Structure-​Based Identification of HIV-​1 Nucleocapsid Protein Inhibitors Active against Wild-​Type and Drug-​Resistant HIV-​1 Strains 24
Dermatological and​/or cosmetic peptides for use in skin treatment 24
Identification of Inhibitors of SARS-CoV-2 3CL-Pro Enzymatic Activity Using a Small Molecule in Vitro Repurposing Screen 24
Nirmatrelvir treatment of SARS-CoV-2-infected mice blunts antiviral adaptive immune responses 23
Discovery of α,​γ-​Diketo Acids as Potent Selective and Reversible Inhibitors of Hepatitis C Virus NS5b RNA-​Dependent RNA Polymerase 23
Preparation of hydroxyoxopyridopyrimidinecarboxamides as HIV integrase inhibitors 23
Characterization and quantification of intact glucosinolates in Catozza rapeseeds: A promising food matrix for nutraceuticals development as a source of hydrogen sulfide 22
Identification of Isoform 2 Acid-Sensing Ion Channel Inhibitors as Tool Compounds for Target Validation Studies in CNS 22
Early metabolic response to acute myocardial ischaemia in patients undergoing elective coronary angioplasty 22
Development of potent macrocyclic inhibitors of genotype 3a HCV NS3​/4A protease 22
Researches on antiviral agents. 4. Studies on the chemistry of 6-​methyl-​2-​methoxy-​4-​O-​acyloxy and 6-​methyl-​2,​4-​di-​O-​acyloxypyrimidine derivatives as new acylation reagents and inhibitors of uracil DNA glycosylases 22
MK-5172, a selective inhibitor of hepatitis C virus NS3/4a protease with broad activity across genotypes and resistant variants 21
Hiv integrase inhibitors 21
Preparation of N-​Ph dicarbamate derivatives as HIV reverse transcriptase inhibitors 21
Preparation of oxalamido-​substituted tricyclic inhibitors of hepatitis B virus 21
Heterocyclic compounds useful in the treatment of disorders that are ameliorated by inhibition of HDAC 20
Approaching a new era for hepatitis C virus therapy: inhibitors of the NS3-​4A serine protease and the NS5B RNA-​dependent RNA polymerase 20
A useful methodology for the regioselective deprotection of 1,​3-​dibenzyluracils 20
Studies of metabolism and disposition of potent human immunodeficiency virus (HIV) integrase inhibitors using 19F-​NMR spectroscopy 20
Phosphorous acid analogs of novel P2-​P4 macrocycles as inhibitors of HCV-​NS3 protease 20
Compositions useful for the treatment of viral diseases 20
Prdm16-mediated H3K9 methylation controls fibro-adipogenic progenitors identity during skeletal muscle repair 20
Agri-Food Waste Recycling for Healthy Remedies: Biomedical Potential of Nutraceuticals from Unripe Tomatoes (Solanum lycopersicum L.) 19
Validation of an LC-MS/MS Method for the Determination of Abscisic Acid Concentration in a Real-World Setting 19
Design, Synthesis, and Biological Evaluation of New 1-(Aryl-1 H-pyrrolyl)(phenyl)methyl-1 H-imidazole Derivatives as Antiprotozoal Agents 19
Preparation of macrocyclic peptides as HCV NS3 protease inhibitors 19
A preparation of tetrahydro-​4H-​pyrido[1,​2-​a]​pyrimidine derivatives, useful as HIV integrase inhibitors 19
Preparation of macrocyclic quinoline and naphthyridine peptides as HCV NS3 protease inhibitors useful in the treatment of hepatitis C infection 19
Preparation of macrocyclic quinoxaline peptide as HCV NS3 protease inhibitor 19
Natural Chalcones for the Management of Obesity Disease 18
A Food-Grade Method for Enhancing the Levels of Low Molecular Weight Proanthocyanidins with Potentially High Intestinal Bioavailability 18
From dihydroxypyrimidine carboxylic acids to carboxamide HIV integrase inhibitors 18
The metabolism and disposition of a potent inhibitor of hepatitis C virus NS3​/4A protease 18
The monoethyl ester of meconic acid is an active site inhibitor of HCV NS5B RNA-​dependent RNA polymerase 18
Discovery of a selective series of inhibitors of Plasmodium falciparum HDACs 18
Inhibitors of the Hepatitis C Virus NS3 Protease with Basic Amine Functionality at the P3-​Amino Acid N-​Terminus: Discovery and Optimization of a New Series of P2-​P4 Macrocycles 18
Preparation of quinazolines as antivirals for treatment of hepatitis C viral (HCV) infection 18
Preparation of 2-​aryldihydroxypyrimidine-​4-​carboxylic acids as hepatitis C viral polymerase inhibitors 18
Identification and in vitro characterization of a new series of potent and highly selective G9a inhibitors as novel anti-fibroadipogenic agents 18
Preparation of macrocyclic peptides as HCV NS3 protease inhibitors 17
VX-​950 vertex​/mitsubishi 17
Synthesis of aryl 2-​benzofuranyl- and 2-​indolyl(aryl)​carbinols of high enantiomeric purity via palladium-​catalyzed heteroannulation of chiral arylpropargylic alcohols 17
Largazole analogues as histone deacetylases inhibitors and anticancer agents: an overview on structure‐activity relationships 17
The synthesis of tetrahydropyridopyrimidones as a new scaffold for HIV-​1 integrase inhibitors 17
Evaluation of HIV-​1 integrase inhibitors on human primary macrophages using a luciferase-​based single-​cycle phenotypic assay 17
Inhibitors of hepatitis C virus NS3​/4A: α-​Ketoamide based macrocyclic inhibitors 17
Structural characterization of the Hepatitis C Virus NS3 protease from genotype 3a: The basis of the genotype 1b vs. 3a inhibitor potency shift 17
Preparation of N-​(4-​fluorobenzyl)​-​5-​hydroxy-​1-​methyl-​2-​(1-​methyl-​1-​[(5-​methyl-​1,​3,​4-​oxadiazol-​2-​yl)​carbonyl]​amino​ethyl)​-​6-​oxo-​1,​6-​dihydropyrimidine-​4-​carboxamide potassium salts as HIV integrase inhibitors 17
Optimization of Ursolic Acid Extraction in Oil from Annurca Apple to Obtain Oleolytes with Potential Cosmeceutical Application 16
Beneficial Contribution to Glucose Homeostasis by an Agro-Food Waste Product Rich in Abscisic Acid: Results from a Randomized Controlled Trial 16
Macrocyclic compounds as antiviral agents 16
Preparation of dihydroxypyrimidine carboxamide inhibitors of HIV integrase 16
Development of macrocyclic inhibitors of HCV NS3​/4A protease with cyclic constrained P2-​P4 linkers 16
Novel P2-​P4 macrocyclic inhibitors of HCV NS3​/4A protease by P3 succinamide fragment depeptidization strategy 16
Routes to HIV-​integrase inhibitors: efficient synthesis of bicyclic pyrimidones by ring expansion or amination at a benzylic position 16
Dihydroxy-​pyrimidine and N-​methylpyrimidone HIV-​integrase inhibitors: Improving cell based activity by the quaternization of a chiral center 16
Discovery, synthesis and optimization of a new series of selective HIV integrase inhibitors leading to MK-​0518 currently in Phase III clinical trial for treatment of HIV​/AIDS 16
Totale 2.587
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Categoria #
all - tutte 17.962
article - articoli 0
book - libri 0
conference - conferenze 0
curatela - curatele 0
other - altro 0
patent - brevetti 0
selected - selezionate 0
volume - volumi 0
Totale 17.962
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Totale Lug Ago Sett Ott Nov Dic Gen Feb Mar Apr Mag Giu
2019/2020135 0 0 0 0 0 12 25 20 3 14 55 6
2020/2021228 9 2 2 0 15 78 32 7 17 5 32 29
2021/2022570 8 4 7 31 16 18 0 36 22 26 88 314
2022/2023657 143 39 10 53 56 49 57 66 112 17 41 14
2023/2024663 47 67 110 69 27 18 21 47 14 25 147 71
2024/2025977 194 343 34 88 145 173 0 0 0 0 0 0
Totale 3.337