IRIS
GALEONE, ALDO
 Distribuzione geografica
Salva come PNG Salva come JPEG
Continente #
AS - Asia 6.439
NA - Nord America 6.195
EU - Europa 5.008
SA - Sud America 822
AF - Africa 163
OC - Oceania 14
AN - Antartide 1
Continente sconosciuto - Info sul continente non disponibili 1
Totale 18.643
Salva come PNG Salva come JPEG
Nazione #
US - Stati Uniti d'America 5.955
SG - Singapore 2.865
RU - Federazione Russa 1.885
IT - Italia 1.343
CN - Cina 1.187
VN - Vietnam 1.171
BR - Brasile 671
HK - Hong Kong 490
UA - Ucraina 299
DE - Germania 296
FR - Francia 226
FI - Finlandia 218
NL - Olanda 159
GB - Regno Unito 138
IE - Irlanda 129
JP - Giappone 129
IN - India 125
CA - Canada 124
SE - Svezia 117
BD - Bangladesh 108
MX - Messico 61
ZA - Sudafrica 58
AR - Argentina 56
PL - Polonia 48
TR - Turchia 40
KR - Corea 36
IQ - Iraq 35
PH - Filippine 33
CI - Costa d'Avorio 32
ID - Indonesia 30
TH - Thailandia 29
EC - Ecuador 28
ES - Italia 27
PK - Pakistan 27
PT - Portogallo 23
CO - Colombia 19
UZ - Uzbekistan 15
BE - Belgio 14
MA - Marocco 14
PY - Paraguay 13
TW - Taiwan 13
AT - Austria 12
AU - Australia 12
CL - Cile 12
IR - Iran 12
VE - Venezuela 12
JM - Giamaica 10
KE - Kenya 10
TN - Tunisia 10
AE - Emirati Arabi Uniti 9
MY - Malesia 9
SA - Arabia Saudita 9
IL - Israele 8
AM - Armenia 7
CR - Costa Rica 7
CZ - Repubblica Ceca 7
DZ - Algeria 7
GT - Guatemala 7
KZ - Kazakistan 7
RO - Romania 7
AZ - Azerbaigian 6
JO - Giordania 6
LT - Lituania 6
PE - Perù 6
DK - Danimarca 5
NI - Nicaragua 5
NP - Nepal 5
BB - Barbados 4
BY - Bielorussia 4
CH - Svizzera 4
DO - Repubblica Dominicana 4
EG - Egitto 4
ET - Etiopia 4
KH - Cambogia 4
MK - Macedonia 4
RS - Serbia 4
SD - Sudan 4
SK - Slovacchia (Repubblica Slovacca) 4
TT - Trinidad e Tobago 4
YE - Yemen 4
BG - Bulgaria 3
EE - Estonia 3
HR - Croazia 3
HU - Ungheria 3
KG - Kirghizistan 3
MD - Moldavia 3
MN - Mongolia 3
MU - Mauritius 3
OM - Oman 3
PA - Panama 3
PR - Porto Rico 3
SI - Slovenia 3
SN - Senegal 3
BA - Bosnia-Erzegovina 2
BH - Bahrain 2
BO - Bolivia 2
GE - Georgia 2
GP - Guadalupe 2
GR - Grecia 2
HN - Honduras 2
Totale 18.604
Salva come PNG Salva come JPEG
Città #
Singapore 1.334
San Jose 847
Chandler 638
Hong Kong 472
Moscow 450
Ashburn 431
Beijing 384
Naples 356
Jacksonville 293
Ho Chi Minh City 292
Hanoi 232
Napoli 214
Santa Clara 196
Los Angeles 178
The Dalles 169
Lauterbourg 155
Princeton 152
Millbury 140
Amsterdam 134
Boston 115
Woodbridge 114
Nanjing 112
Dong Ket 94
Tokyo 90
Buffalo 88
Hefei 85
New York 81
Council Bluffs 73
Wilmington 70
Ann Arbor 69
Houston 67
Munich 67
Da Nang 60
São Paulo 55
Haiphong 53
Orem 46
Ottawa 46
Redondo Beach 45
Dallas 43
Seattle 40
Des Moines 36
Nanchang 34
Turku 34
Hebei 33
Milan 33
Brooklyn 30
Frankfurt am Main 29
Warsaw 29
Helsinki 28
Portici 28
Rio de Janeiro 28
Shenyang 28
Denver 26
Montreal 26
Norwalk 26
Rome 26
Tianjin 26
Biên Hòa 24
Chicago 24
Phoenix 24
Mexico City 23
Chennai 22
Dearborn 22
Jiaxing 22
Toronto 22
Falls Church 21
Atlanta 19
Johannesburg 18
London 18
Poplar 18
San Francisco 18
Manchester 17
Mumbai 17
Paris 16
Baghdad 15
Changsha 15
Hangzhou 15
Lawrence 15
Stockholm 15
Ankara 14
Belo Horizonte 14
Boardman 14
Kronberg 14
Washington 14
Augusta 13
Bangkok 13
Can Tho 13
Formia 13
Salerno 13
Brasília 12
Falkenstein 12
Ninh Bình 12
Pune 12
Salvador 12
Tashkent 12
Charlotte 11
Guangzhou 11
Nuremberg 11
Poznan 11
Redwood City 11
Totale 9.762
Salva come PNG Salva come JPEG
Nome #
Pyrimido[5,4-d]Pyrimidine or pyrimidine derivates compounds and uses there of in the treatment of cancer 218
Ptaquiloside, the major carcinogen of bracken fern, in the pooled raw milk of healthy sheep and goats: an underestimated, global concern of food safety 194
Structural and biological properties of novel G4-aptamer-drug conjugates as a vehicle for 5-fluoro-2′-deoxyuridine 170
A bunch-oligonucleotide forming stable monomolecular quadruplex containing a T-tetrad. 163
Metastatic group 3 medulloblastoma is driven by PRUNE1 targeting NME1-TGF-β-OTX2-SNAIL via PTEN inhibition. 163
Properties and Potential Antiproliferative Activity of Thrombin-Binding Aptamer (TBA) Derivatives with One or Two Additional G-Tetrads 161
Antiproliferative Effects of the Aptamer d(GGGT) 4 and Its Analogues with an Abasic-Site Mimic Loop on Different Cancer Cells 160
The ‘‘Janus face” of the thrombin binding aptamer: Investigating the anticoagulant and antiproliferative properties through straightforward chemical modifications 151
From protein-protein interaction to E2 inhibitors leads: identification of peptide binding of UbcH10 149
Quadruplex DNA: structural features and potential applications 149
PROBING THE EFFECTS OF CHEMICAL MODIFICATIONS ON THROMBIN BINDING APTAMER BIOLOGICAL ACTIVITY. 149
Backbone modified TBA analogues endowed with antiproliferative activity 148
5-Hydroxymethyl-2′-Deoxyuridine Residues in the Thrombin Binding Aptamer: Investigating Anticoagulant Activity by Making a Tiny Chemical Modification 147
Site specific replacements of a single loop nucleoside with a dibenzyl linker may switch the activity of TBA from anticoagulant to antiproliferative 147
1H-NMR study of the quadruplex [d(TGGGT)]4 containing a modified thymine 146
New G-quadruplex DNA catalysts in enantioselective sulfoxidation reaction 144
MicroRNA 199b-5p delivery through stable nucleic acid lipid particles (SNALPs) in tumorigenic cell lines 144
A straightforward modification in the thrombin binding aptamer improving stability, affinity to thrombin and nuclease resistance 144
EFFECT OF THE INTRODUCTION OF AN A-RESIDUE INTO A QUADRUPLEX FORMING OLIGONUCLEOTIDE CONTAINING A 5'-5' POLARITY OF INVERSION SITE 143
Synthesis, structural studies and biological properties of new TBA analogues containing an acyclic nucleotide 143
Structural Model of the hUbA1-UbcH10 Quaternary Complex: In Silico and Experimental Analysis of the Protein-Protein Interactions between E1, E2 and Ubiquitin 142
A topological classification of G-quadruplex structures 141
Molecular Modelling Studies of Four Stranded Quadruplexes Containing a 3’-3’ or 5’-5’ Inversion of Polarity Site 141
UL3 mediated nucleolar stress pathway as a new mechanism of action of antiproliferative G-quadruplex TBA derivatives in colon cancer cells 140
Synthesis and characterization of tetra-end linked oligonucleotides capable of forming monomolecular G-quadruplex 139
Aspetti dell’interazione tra la distamicina-A e la quadruplex [d(TGGGGT)]4 139
Novel pyrimidopyrimidine derivatives for inhibition of cellular proliferation and motility induced by h-prune in breast cancer 137
Heterochiral oligodeoxynucleotides forming quadruplex structures 137
1H-NMR Study of the Quadruplex [d(TGGGT)]4 Containing a Modified Thymine 135
A NEW CLASS OF DNA QUADRUPLEX FORMED BY OLIGODEOXYRIBONUCLEOTIDES CONTAINING A 3’-3’ OR 5’-5’ INVERSION OF POLARITY SITE 134
Thrombin-Binding Aptamer (TBA) derivatives with one or two additional G-Tetrads: properties and potential antiproliferative activity 133
Synthesis and structural study of quadruplex structures containing 2'-deoxy-8-methyladenosine 132
Expanding the potential of G-quadruplex structures: formation of a heterochiral TBA analogue 132
8-Methyl-2'-deoxyguanosine incorporation into parallel DNA quadruplex structures 131
Studio 1H-NMR dell’ interazione tra la distamicina A e la netropsina con strutture di duplex e quadruplex DNA 131
PRELIMINARY STRUCTURAL INVESTIGATIONS ON THE ANTI-HIV G-QUADRUPLEX FORMING OLIGONUCLEOTIDE TGGGAG AND ANALOGUES: EVIDENCE FOR THE PRESENCE OF AN A-TETRAD 131
Structural properties and anticoagulant/cytotoxic activities of heterochiral enantiomeric thrombin binding aptamer (TBA) derivatives 130
A MINI-LIBRARY OF TBA ANALOGUES CONTAINING 3'-3' AND 5'-5' INVERSION OF POLARITY SITES 129
G-triplex stability in human telomeric DNA with epigenetic modification/oxidative damage to thymine 129
Discovering New G-Quadruplex DNA Catalysts in Enantioselective Sulfoxidation Reaction 129
Introduzione alla chimica organica 127
A NEW CLASS OF DNA QUADRUPLEX FORMED BY OLIGODEOXYRIBONUCLEOTIDES CONTAINING A 3'-3' OR 5'-5' INVERSION OF POLARITY SITE 127
Monomolecular G-quadruplex structures with inversion of polarity sites: new topologies and potentiality 127
G-Quadruplex aptamer T30175 and its derivatives: exploring new potential anticancer activities 126
MiR-34a Targeting of Notch Ligand Delta-Like 1 ImpairsCD15+/CD133+ Tumor-Propagating Cells and SupportsNeural Differentiation in 126
MicroRNA-199b-5p impairs cancer stem cells through negative regulation of HES1 in medulloblastoma. 126
Exploring the binding of d(GGGT)4 to the HIV-1 integrase: An approach to investigate G-quadruplex aptamer/target protein interactions. 126
Heterochiral oligodeoxynucleotides forming quadruplex structures 125
Solid phase approach to the preparation of small circular DNA and RNA fragments 124
Unusual Chair-Like G-Quadruplex Structures: Heterochiral TBA Analogues Containing Inversion of Polarity Sites 123
Studio di strutture cruciformi mediante NMR 123
Probing the Effects of Chemical Modifications on Anticoagulant and Antiproliferative Activity of Thrombin Binding Aptamer 122
Syntheses of [1-15N]-2'-deoxyinosine, [4-15N]-2'-deoxyAICAR, and [1-15N]-2'-deoxyguanosine. 122
Structural and thermodynamic studies of the interaction of distamycin A with the parallel quadruplex structure [d(TGGGGT)]4 122
Effects of abasic sites on structural, thermodynamic and kinetic properties of quadruplex structures. 122
Chimica Organica 121
Improvement of the activity of the anti-HIV-1 integrase aptamer T30175 by introducing a modified thymidine into the loops 121
Physico-chemical studies of quadruple helices of modified human telomeric DNA 120
The abasic site lesions in the human telomeric sequence d[TA(G3T2A)3G3]: A thermodynamic point of view 120
Effects of 8-methylguanine on structure, stability and kinetics of formation of tetramolecular quadruplexes 120
Homology building, protein-protein docking and MD approach to the simulation of the quaternary complex E1/E2/Ub2 119
NMR STUDIES ON QUADRUPLEX STRUCTURES CONTAINING ABASIC SITES 119
Thrombin binding aptamer analogues containing inversion of polarity sites endowed with antiproliferative and anti-motility properties against Calu-6 cells 119
Structural and Biological Features of G-Quadruplex Aptamers as Promising Inhibitors of the STAT3 Signaling Pathway 119
EFFECT OF GUANINE BASES MODIFICATIONS AND L-DNA ON STABILITY AND KINETIC OF FORMATION OF TETRAMOLECULAR QUADRUPLEXES 117
THE ABASIC SITE LESIONS IN THE HUMAN TELOMERIC SEQUENCE d[TA(G3T2A)3G3]: A THERMODYNAMIC POINT OF VIEW 117
Site-specific replacement of the thymine methyl group by fluorine in thrombin binding aptamer significantly improves structural stability and anticoagulant activity 117
Exploring New Potential Anticancer Activities of the G-Quadruplexes Formed by [(GTG2T(G3T)3] and Its Derivatives with an Abasic Site Replacing Single Thymidine 117
Synthesis of 5-methylamino-2'-deoxyuridine derivatives. 115
1H and 13C NMR spectra of imidazo[1,2-a]pyrazines. 115
Bunchy oligonucleotides forming new stable DNA quadruplex structure 115
2'-Deoxy-8-(propyn-1-yl)adenosine-containing oligonucleotides: effects on stability of duplex and quadruplex structures 114
Solid phase synthesis of cyclic oligodeoxyribonucleotides intermolecular versus intramolecular coupling. 114
Homology building, protein-protein docking and MD approach to the simulation of the quaternary complex E1/E2/Ub2. 114
PRELIMINARY STRUCTURAL INVESTIGATIONS ON THE ANTI-HIV G-QUADRUPLEX FORMING OLIGONUCLEOTIDE TGGGAG AND ANALOGUES: EVIDENCE FOR THE PRESENCE OF AN A-TETRAD 113
Biophysical properties of quadruple helices of modified human telomeric DNA 111
Oligonucleotidi contenenti 2’-deossi-8-(1—propinil)-Adenosina: stabilità delle strutture quadruplex. 110
Improved thrombin binding aptamer analogues containing inversion of polarity sites: structural effects of extra-residues at the ends 110
The oxidative damage to the human telomere: effects of 5-hydroxymethyl-2'-deoxyuridine on telomeric G-quadruplex structures 109
NUOVI INIBITORI PIRIMIDO-PIRIMIDINICI DELL'ATTIVITA' FOSFODIESTERASICA PRO-METASTASI DI H-PRUNE 109
Transferrin-conjugated SNALPs encapsulating 2'-O-methylated miR-34a for the treatment of multiple myeloma. 109
Aptamers against the β-conglutin allergen: Insights into the behavior of the shortest multimeric (intra)molecular dna gquadruplex 109
A new class of DNA quadruplexes formed by oligodeoxyribonucleotides containing a 3'-3' or 5'-5' inversion of polarity site 108
Synthesis of 3'-3'-linked pyrimidine oligonucleotides containing an acridine moiety for alternate strand triple helix formation 108
Aptamer-Drug conjugates for a targeted and synergistic anticancer Response: Exploiting T30923-5-fluoro-2′-deoxyuridine (INT-FdU) derivatives 107
Circular dichroism and termal melting differentiation of Hoechst 33258 bindings to the curved (A4T4) and non curved (T4A4) DNA sequences. 107
Synthesis and characterization of poly(dl-lactic acid)-idoxuridine conjugate. 107
PNA-DNA chimeras forming quadruplex structures 107
Automated solid phase synthesis of cyclic oligonucleotides: a further improvement 107
Design, synthesis, biophysical and biological studies on trisubstituted naphthalimides as G-Quadruplex ligands 107
The insertion of two 8-methyl-2'-deoxyguanosineresidues in tetramolecular quadruplex structures:trying to orientate the strands 107
A further contribution to the extreme variability of quadruplex structures from oligodeoxyribonucleotides containing inversion of polarity sites in the G-tract 106
EFFECTS OF THE SYN/ANTI EQUILIBRIUM MODULATION ON THE STRUCTURAL PROPERTIES OF TETRAMOLECULAR QUADRUPLEXES, 106
GLI EFFETTI DELL’INTRODUZIONE DI SITI DI INVERSIONE DELLA POLARITA’ SULLA STRUTTURA QUADRUPLEX DEL DNA (TGGGT)4 106
A novel pyrimidine tetrad contributing to stabilize tetramolecular G-quadruplex structures. 106
Binding mode of distamycin to d(CGTACGTACG)2 in the 2:1 solution complex as determined by two-dimensional 1H NMR and molecular modeling studies 105
Synthesis of triple helix forming oligonucleotides with a phenanthroline moiety into the 3’-3’ inversion site of polarity 105
Investigating the properties of TBA variants with twin thrombin binding domains 105
Improving the Biological Properties of Thrombin-Binding Aptamer by Incorporation of 8-Bromo-2′-Deoxyguanosine and 2′-Substituted RNA Analogues 104
Structural study of four-stranded quadruplex structures containing 2'-deoxy-8-(propyn-1-yl)adenosine 104
Totale 12.718
Salva come PNG Salva come JPEG
Categoria #
all - tutte 61.699
article - articoli 0
book - libri 0
conference - conferenze 0
curatela - curatele 0
other - altro 0
patent - brevetti 0
selected - selezionate 0
volume - volumi 0
Totale 61.699
Salva come PNG Salva come JPEG


Totale Lug Ago Sett Ott Nov Dic Gen Feb Mar Apr Mag Giu
2021/2022956 15 2 15 13 12 65 6 50 145 126 166 341
2022/20231.403 206 105 35 194 124 182 7 155 176 134 69 16
2023/2024753 26 134 92 41 40 58 27 107 12 17 143 56
2024/20254.255 223 265 13 25 160 169 517 247 333 417 1.533 353
2025/20268.714 893 661 885 783 1.559 283 868 587 1.086 575 245 289
2026/2027130 130 0 0 0 0 0 0 0 0 0 0 0
Totale 19.091