IRIS
GALEONE, ALDO
 Distribuzione geografica
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Continente #
NA - Nord America 3.084
EU - Europa 2.002
AS - Asia 1.093
AF - Africa 37
OC - Oceania 10
SA - Sud America 8
Totale 6.234
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Nazione #
US - Stati Uniti d'America 3.031
IT - Italia 954
SG - Singapore 506
CN - Cina 386
UA - Ucraina 274
FI - Finlandia 149
DE - Germania 130
IE - Irlanda 123
NL - Olanda 123
SE - Svezia 100
VN - Vietnam 95
GB - Regno Unito 52
CA - Canada 50
IN - India 34
CI - Costa d'Avorio 32
JP - Giappone 24
FR - Francia 21
TR - Turchia 17
PL - Polonia 13
AU - Australia 10
BE - Belgio 10
PT - Portogallo 10
HK - Hong Kong 9
IR - Iran 9
CZ - Repubblica Ceca 7
CL - Cile 6
ES - Italia 6
DK - Danimarca 5
CH - Svizzera 4
PK - Pakistan 4
RU - Federazione Russa 4
AM - Armenia 3
SD - Sudan 3
TW - Taiwan 3
AT - Austria 2
CR - Costa Rica 2
EE - Estonia 2
HU - Ungheria 2
KR - Corea 2
SI - Slovenia 2
SK - Slovacchia (Repubblica Slovacca) 2
AL - Albania 1
BG - Bulgaria 1
BR - Brasile 1
LT - Lituania 1
MA - Marocco 1
MD - Moldavia 1
MT - Malta 1
MY - Malesia 1
PR - Porto Rico 1
PY - Paraguay 1
RO - Romania 1
RS - Serbia 1
ZA - Sudafrica 1
Totale 6.234
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Città #
Chandler 637
Singapore 424
Jacksonville 289
Napoli 214
Naples 176
Princeton 152
Millbury 140
Ashburn 129
Amsterdam 119
Woodbridge 113
Nanjing 110
Dong Ket 94
Boston 91
Santa Clara 91
Beijing 74
Wilmington 70
Ann Arbor 69
Houston 58
Ottawa 42
Des Moines 35
Nanchang 34
Hebei 33
Norwalk 26
Shenyang 26
Dearborn 22
Jiaxing 22
Falls Church 21
Tianjin 18
Hangzhou 15
Boardman 14
Kronberg 14
Lawrence 14
Formia 13
Augusta 12
Milan 12
Rome 12
Changsha 11
Poznan 11
Redwood City 11
Marano Di Napoli 10
Washington 10
Caserta 9
Los Angeles 9
Orange 9
Paris 9
Salerno 9
Seattle 9
Brisbane 8
Hong Kong 8
Nocera Inferiore 8
Portici 8
New York 7
Pune 7
Brno 6
Edinburgh 6
Aarhus 5
Cercola 5
Dublin 5
Giugliano in Campania 5
Guangzhou 5
Padova 5
San Mateo 5
Turin 5
Arzano 4
Brussels 4
Hyderabad 4
Indiana 4
Kharagpur 4
Roccarainola 4
San Francisco 4
San Giorgio A Cremano 4
Simi Valley 4
Toronto 4
Torre del Greco 4
Acerra 3
Ardabil 3
Aveiro 3
Bologna 3
Braga 3
Brusciano 3
Cambridge 3
Casalvieri 3
Casoria 3
Dallas 3
Fairfield 3
Grumo Nevano 3
Kanazawa 3
Kunming 3
Leawood 3
Padula 3
Piana 3
Rohtak 3
San Giorgio 3
Torino 3
Vietri Sul Mare 3
Yerevan 3
Zhengzhou 3
Abidjan 2
Aszod 2
Avellino 2
Totale 3.759
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Nome #
Ptaquiloside, the major carcinogen of bracken fern, in the pooled raw milk of healthy sheep and goats: an underestimated, global concern of food safety 91
Pyrimido[5,4-d]Pyrimidine or pyrimidine derivates compounds and uses there of in the treatment of cancer 89
The ‘‘Janus face” of the thrombin binding aptamer: Investigating the anticoagulant and antiproliferative properties through straightforward chemical modifications 89
Backbone modified TBA analogues endowed with antiproliferative activity 86
Unusual Chair-Like G-Quadruplex Structures: Heterochiral TBA Analogues Containing Inversion of Polarity Sites 75
Thrombin binding aptamer analogues containing inversion of polarity sites endowed with antiproliferative and anti-motility properties against Calu-6 cells 73
EFFECT OF THE INTRODUCTION OF AN A-RESIDUE INTO A QUADRUPLEX FORMING OLIGONUCLEOTIDE CONTAINING A 5'-5' POLARITY OF INVERSION SITE 70
Metastatic group 3 medulloblastoma is driven by PRUNE1 targeting NME1-TGF-β-OTX2-SNAIL via PTEN inhibition. 70
Synthesis and characterization of tetra-end linked oligonucleotides capable of forming monomolecular G-quadruplex 66
1H-NMR study of the quadruplex [d(TGGGT)]4 containing a modified thymine 65
5-Hydroxymethyl-2′-Deoxyuridine Residues in the Thrombin Binding Aptamer: Investigating Anticoagulant Activity by Making a Tiny Chemical Modification 65
8-Methyl-2'-deoxyguanosine incorporation into parallel DNA quadruplex structures 63
The oxidative damage to the human telomere: effects of 5-hydroxymethyl-2'-deoxyuridine on telomeric G-quadruplex structures 60
Site specific replacements of a single loop nucleoside with a dibenzyl linker may switch the activity of TBA from anticoagulant to antiproliferative 60
Site-specific replacement of the thymine methyl group by fluorine in thrombin binding aptamer significantly improves structural stability and anticoagulant activity 60
Monomolecular G-quadruplex structures with inversion of polarity sites: new topologies and potentiality 60
Aptamers against the β-conglutin allergen: Insights into the behavior of the shortest multimeric (intra)molecular dna gquadruplex 60
UL3 mediated nucleolar stress pathway as a new mechanism of action of antiproliferative G-quadruplex TBA derivatives in colon cancer cells 59
A topological classification of G-quadruplex structures 57
Automated solid phase synthesis of cyclic oligonucleotides: a further improvement 57
Aspetti dell’interazione tra la distamicina-A e la quadruplex [d(TGGGGT)]4 57
A bunch-oligonucleotide forming stable monomolecular quadruplex containing a T-tetrad. 57
Molecular Modelling Studies of Four Stranded Quadruplexes Containing a 3’-3’ or 5’-5’ Inversion of Polarity Site 56
Introduzione alla chimica organica 56
MicroRNA 199b-5p delivery through stable nucleic acid lipid particles (SNALPs) in tumorigenic cell lines 56
A novel pyrimidine tetrad contributing to stabilize tetramolecular G-quadruplex structures. 56
G-triplex stability in human telomeric DNA with epigenetic modification/oxidative damage to thymine 56
A MINI-LIBRARY OF TBA ANALOGUES CONTAINING 3'-3' AND 5'-5' INVERSION OF POLARITY SITES 54
Solid phase synthesis of cyclic oligodeoxyribonucleotides intermolecular versus intramolecular coupling. 53
Synthesis of 3'-3'-linked pyrimidine oligonucleotides containing an acridine moiety for alternate strand triple helix formation 53
Quadruplex DNA: structural features and potential applications 53
1H-NMR Study of the Quadruplex [d(TGGGT)]4 Containing a Modified Thymine 53
Antiproliferative Effects of the Aptamer d(GGGT) 4 and Its Analogues with an Abasic-Site Mimic Loop on Different Cancer Cells 52
Structural and thermodynamic studies of the interaction of distamycin A with the parallel quadruplex structure [d(TGGGGT)]4 52
Synthesis, structural studies and biological properties of new TBA analogues containing an acyclic nucleotide 52
Design, synthesis, biophysical and biological studies on trisubstituted naphthalimides as G-Quadruplex ligands 52
nmr studies of the 5-(hydroxymethyl-2'-deoxyuridine containing tf1 binding site 51
Discovering New G-Quadruplex DNA Catalysts in Enantioselective Sulfoxidation Reaction 51
Solid phase synthesis of 5-hydroxymethyluracil containing DNA 49
2'-Deoxy-8-(propyn-1-yl)adenosine-containing oligonucleotides: effects on stability of duplex and quadruplex structures 49
A new class of DNA quadruplexes formed by oligodeoxyribonucleotides containing a 3'-3' or 5'-5' inversion of polarity site 48
A bunch-oligonucleotide forming stable monomolecular quadruplex containing a T-tetrad 48
The abasic site lesions in the human telomeric sequence d[TA(G3T2A)3G3]: A thermodynamic point of view 48
Syntheses of [1-15N]-2'-deoxyinosine, [4-15N]-2'-deoxyAICAR, and [1-15N]-2'-deoxyguanosine. 47
Studio 1H-NMR dell’ interazione tra la distamicina A e la netropsina con strutture di duplex e quadruplex DNA 47
A NEW CLASS OF DNA QUADRUPLEX FORMED BY OLIGODEOXYRIBONUCLEOTIDES CONTAINING A 3’-3’ OR 5’-5’ INVERSION OF POLARITY SITE 47
Expanding the potential of G-quadruplex structures: formation of a heterochiral TBA analogue 47
Solid phase approach to the preparation of small circular DNA and RNA fragments 46
1H-NMR study of the interaction of distamycin A and netropsin with the parallel stranded tetraplex [d(TGGGGT)]4. 46
1H and 13C NMR spectra of imidazo[1,2-a]pyrazines. 44
Effects of 8-Methyl-2'-deoxyadenosine incorporation into quadruplex forming oligonucleotides 44
A NEW CLASS OF DNA QUADRUPLEX FORMED BY OLIGODEOXYRIBONUCLEOTIDES CONTAINING A 3'-3' OR 5'-5' INVERSION OF POLARITY SITE 44
A straightforward modification in the thrombin binding aptamer improving stability, affinity to thrombin and nuclease resistance 44
Effects of 8-methylguanine on structure, stability and kinetics of formation of tetramolecular quadruplexes 44
The Introduction of Inversion of Polarity Sites in DNA G-Quadruplex Structures: Effects and Perspectives 44
Exploring the binding of d(GGGT)4 to the HIV-1 integrase: An approach to investigate G-quadruplex aptamer/target protein interactions. 44
Synthesis and structural study of quadruplex structures containing 2'-deoxy-8-methyladenosine 43
Synthesis and Characterization of monomolecular DNA G-quadruplex formed by tetra-end-linked oligonucleotides 43
PRELIMINARY STRUCTURAL INVESTIGATIONS ON THE ANTI-HIV G-QUADRUPLEX FORMING OLIGONUCLEOTIDE TGGGAG AND ANALOGUES: EVIDENCE FOR THE PRESENCE OF AN A-TETRAD 43
Improved thrombin binding aptamer analogues containing inversion of polarity sites: structural effects of extra-residues at the ends 43
Improvement of the activity of the anti-HIV-1 integrase aptamer T30175 by introducing a modified thymidine into the loops 43
Structural properties and anticoagulant/cytotoxic activities of heterochiral enantiomeric thrombin binding aptamer (TBA) derivatives 43
Unusual monomolecular DNA Quadruplex structures using bunch-oligonucleotides 42
Facile preparation of cyclic oligoribonucleotides. 42
Binding mode of distamycin to d(CGTACGTACG)2 in the 2:1 solution complex as determined by two-dimensional 1H NMR and molecular modeling studies 42
PNA-DNA chimeras forming quadruplex structures 42
Chimica Organica 42
Investigating the properties of TBA variants with twin thrombin binding domains 42
Synthesis of 5-methylamino-2'-deoxyuridine derivatives. 41
Exploring New Potential Anticancer Activities of the G-Quadruplexes Formed by [(GTG2T(G3T)3] and Its Derivatives with an Abasic Site Replacing Single Thymidine 41
Circular dichroism and termal melting differentiation of Hoechst 33258 bindings to the curved (A4T4) and non curved (T4A4) DNA sequences. 40
Effects of abasic sites on structural, thermodynamic and kinetic properties of quadruplex structures. 40
NUOVI INIBITORI PIRIMIDO-PIRIMIDINICI DELL'ATTIVITA' FOSFODIESTERASICA PRO-METASTASI DI H-PRUNE 40
Easy chemical modifications to explore the ‘Janus face’ of TBA: anticoagulant vs antiproliferative properties. 40
Interaction of Distamycin A and Netropsin with Quadruplex and Duplex Structures: a Comparative 1H-NMR study 39
Oligonucleotide delivery in cancer therapy 39
The insertion of two 8-methyl-2'-deoxyguanosineresidues in tetramolecular quadruplex structures:trying to orientate the strands 39
Trisubstituted naphthalimides for DNA quadruplex binding selectivity: synthesis, NMR and biophysical studies 39
Structural Model of the hUbA1-UbcH10 Quaternary Complex: In Silico and Experimental Analysis of the Protein-Protein Interactions between E1, E2 and Ubiquitin 39
Structural study of four-stranded quadruplex structures containing 2'-deoxy-8-(propyn-1-yl)adenosine 38
Bunchy oligonucleotides forming new stable DNA quadruplex structure 38
Synthesis of triple helix forming oligonucleotides with a phenanthroline moiety into the 3’-3’ inversion site of polarity 37
Physico-chemical studies of quadruple helices of modified human telomeric DNA 37
MicroRNA-199b-5p impairs cancer stem cells through negative regulation of HES1 in medulloblastoma. 37
From protein-protein interaction to E2 inhibitors leads: identification of peptide binding of UbcH10 37
Improved performances of catalytic G-quadruplexes (G4-DNAzymes) via the chemical modifications of the DNA backbone to provide Gquadruplexes with double 3′-external G-quartets 37
Slow conformational exchange in DNA minihairpin loops: a conformational study of the circular dumbbell d 36
Quadruplex DNA: structural features and potential applications 36
Tetra-end-linked oligonucleotides forming DNA G-quadruplexes: a new class of aptamers showing anti-HIV activity 36
Novel pyrimidopyrimidine derivatives for inhibition of cellular proliferation and motility induced by h-prune in breast cancer 36
EFFECTS OF THE SYN/ANTI EQUILIBRIUM MODULATION ON THE STRUCTURAL PROPERTIES OF TETRAMOLECULAR QUADRUPLEXES, 36
Effect of gamma-hydroxypropano deoxyguanosine, the major acrolein-derived adduct, on monomolecular quadruplex structure of telomeric repeat d(TTAGGG) 4 36
Studies on alternate strand triple helix formation by oligodeoxyribonucleotides containing a 3'-3' phosphodiester bond. 35
Synthesis and characterization of a bunchy oligonucleotide forming a monomolecular parallel quadruplex structure in solution. 35
A further contribution to the extreme variability of quadruplex structures from oligodeoxyribonucleotides containing inversion of polarity sites in the G-tract 35
Heterochiral oligodeoxynucleotides forming quadruplex structures 35
Heterochiral oligodeoxynucleotides forming quadruplex structures 35
Structural and biological properties of novel G4-aptamer-drug conjugates as a vehicle for 5-fluoro-2′-deoxyuridine 34
Affinity, stability and polarity of binding of the TATA binding protein governed by flexure at the TATA box. 34
Formulazione costituita da snalp contenente pre-mir 34a utile per il trattamento del mieloma multiplo 34
Totale 4.876
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Categoria #
all - tutte 27.791
article - articoli 0
book - libri 0
conference - conferenze 0
curatela - curatele 0
other - altro 0
patent - brevetti 0
selected - selezionate 0
volume - volumi 0
Totale 27.791
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Totale Lug Ago Sett Ott Nov Dic Gen Feb Mar Apr Mag Giu
2019/2020375 0 0 0 0 96 20 38 5 15 42 71 88
2020/2021909 16 62 84 65 110 119 74 20 138 12 98 111
2021/2022956 15 2 15 13 12 65 6 50 145 126 166 341
2022/20231.403 206 105 35 194 124 182 7 155 176 134 69 16
2023/2024753 26 134 92 41 40 58 27 107 12 17 143 56
2024/2025678 223 265 13 25 152 0 0 0 0 0 0 0
Totale 6.670