IRIS
PICCIALLI, GENNARO
 Distribuzione geografica
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Continente #
AS - Asia 10.387
NA - Nord America 9.730
EU - Europa 8.062
SA - Sud America 1.405
Continente sconosciuto - Info sul continente non disponibili 445
AF - Africa 244
OC - Oceania 26
Totale 30.299
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Nazione #
US - Stati Uniti d'America 9.298
SG - Singapore 4.628
RU - Federazione Russa 3.043
IT - Italia 2.119
CN - Cina 1.937
VN - Vietnam 1.910
BR - Brasile 1.136
HK - Hong Kong 708
DE - Germania 484
UA - Ucraina 482
FR - Francia 393
FI - Finlandia 374
CA - Canada 257
GB - Regno Unito 245
BD - Bangladesh 240
IE - Irlanda 227
NL - Olanda 226
JP - Giappone 180
IN - India 177
SE - Svezia 138
AR - Argentina 110
MX - Messico 91
PL - Polonia 87
KR - Corea 82
ZA - Sudafrica 80
TR - Turchia 70
IQ - Iraq 60
PH - Filippine 57
CI - Costa d'Avorio 55
ES - Italia 48
TH - Thailandia 46
PK - Pakistan 39
EC - Ecuador 37
ID - Indonesia 36
AT - Austria 34
CO - Colombia 34
TW - Taiwan 30
VE - Venezuela 26
UZ - Uzbekistan 23
LT - Lituania 21
CH - Svizzera 20
IR - Iran 20
CZ - Repubblica Ceca 18
JM - Giamaica 17
PE - Perù 17
AU - Australia 15
BE - Belgio 15
JO - Giordania 15
AZ - Azerbaigian 14
CL - Cile 14
EG - Egitto 14
PY - Paraguay 14
CR - Costa Rica 13
MA - Marocco 13
MY - Malesia 12
SA - Arabia Saudita 12
AE - Emirati Arabi Uniti 11
IL - Israele 11
BG - Bulgaria 10
NP - Nepal 10
TN - Tunisia 10
DZ - Algeria 9
GE - Georgia 9
KE - Kenya 9
AL - Albania 8
HN - Honduras 8
PT - Portogallo 8
SY - Repubblica araba siriana 8
TT - Trinidad e Tobago 8
UY - Uruguay 8
DK - Danimarca 7
KG - Kirghizistan 7
RS - Serbia 7
BO - Bolivia 6
DO - Repubblica Dominicana 6
EU - Europa 6
LB - Libano 6
NG - Nigeria 6
BA - Bosnia-Erzegovina 5
BB - Barbados 5
ET - Etiopia 5
NI - Nicaragua 5
OM - Oman 5
PA - Panama 5
RO - Romania 5
BW - Botswana 4
BY - Bielorussia 4
MD - Moldavia 4
PS - Palestinian Territory 4
SN - Senegal 4
AM - Armenia 3
CV - Capo Verde 3
EE - Estonia 3
GR - Grecia 3
GT - Guatemala 3
KZ - Kazakistan 3
LC - Santa Lucia 3
LU - Lussemburgo 3
LV - Lettonia 3
MK - Macedonia 3
Totale 29.774
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Città #
Singapore 2.171
San Jose 1.286
Chandler 818
Moscow 745
Hong Kong 696
Ashburn 651
Beijing 626
Ho Chi Minh City 529
Naples 485
Jacksonville 456
Hanoi 417
Napoli 355
Los Angeles 290
Santa Clara 272
Lauterbourg 253
The Dalles 240
Millbury 239
Hefei 237
Woodbridge 225
Princeton 221
Houston 204
Amsterdam 185
Boston 155
Buffalo 154
Tokyo 153
Munich 150
Nanjing 148
New York 142
Ottawa 125
São Paulo 123
Dallas 108
Dong Ket 100
Council Bluffs 93
Wilmington 92
Helsinki 90
Milan 80
Ann Arbor 78
Haiphong 76
Redondo Beach 74
Warsaw 74
Da Nang 73
Orem 62
Rome 62
Des Moines 56
Brooklyn 54
Chicago 53
Montreal 53
Seattle 53
Turku 52
Denver 50
Norwalk 46
Nanchang 45
Portici 45
Johannesburg 43
London 42
San Francisco 41
Frankfurt am Main 40
Hebei 40
Rio de Janeiro 40
Seoul 40
Shenyang 40
Chennai 39
Phoenix 38
Poplar 38
Mexico City 36
Tianjin 36
Atlanta 34
Stockholm 34
Biên Hòa 32
Palermo 32
Jiaxing 30
Belo Horizonte 29
Falkenstein 28
Manchester 27
Baghdad 26
Changsha 26
Dhaka 26
Nuremberg 26
Lawrence 24
Pune 23
Toronto 23
Guangzhou 22
Ankara 21
Boardman 21
Caserta 21
Lappeenranta 20
Can Tho 19
Mumbai 19
Bangkok 18
Catania 17
Charlotte 17
Curitiba 17
Falls Church 17
Miami 17
Orange 17
Sarno 17
Tashkent 17
Dublin 16
Düsseldorf 16
Bogotá 15
Totale 15.597
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Nome #
Investigating the Role of T7 and T12 Residues on the Biological Properties of Thrombin-Binding Aptamer 251
Anti-HIV activity of new higher order G-quadruplex aptamers obtained from tetra-end-linked oligonucleotides 197
Peptide Nucleic Acid-Functionalized Adenoviral Vectors Targeting G-Quadruplexes in the P1 Promoter of Bcl-2 Proto-Oncogene: A New Tool for Gene Modulation in Anticancer Therapy 197
Screening Platform toward New Anti-HIV Aptamers Set on Molecular Docking and Fluorescence Quenching Techniques 195
Carbohydrate-modified Hydrosilylated Porous Silicon Nanoparticles via one-pot Passivation-Functionalization Chemical Strategy for Biomedical Applications 180
PNA-Based Porous Silicon Biosensor: Towards a Label-Free Optical Assay for Myocardial infarction 175
Evaluation of an Analogue of the Marine ε-PLL Peptide as a Ligand of G-quadruplex DNA Structures 173
Exploring the DNA2-PNA heterotriplex formation in targeting the Bcl-2 gene promoter: A structural insight by physico-chemical and microsecond-scale MD investigation 172
New G-quadruplex-forming oligodeoxynucleotides incorporating a bifunctional double-ended linker (DEL): Effects of del size and ODNs orientation on the topology, stability, and molecularity of del-G-quadruplexes 168
Oncolytic adenovirus loaded with L-carnosine as a drug delivery system for cancer therapy. 167
Exploring the Role of Chirality in the Ca2+ Mobilizing Properties of New cADPR Linear Precursors 165
A bunch-oligonucleotide forming stable monomolecular quadruplex containing a T-tetrad. 164
Peptide Nucleic Acids as miRNA Target Protectors for the Treatment of Cystic Fibrosis 162
Anti HIV activity of monomolecular tetra-end-linked analogues of the SA-1042 aptamer targeted against the viral envelope glycoprotein gp120 161
Degradation of some representative polycyclic aromatic hydrocarbons by the water-soluble protein extracts from Zea mays L. cv PR32-B10 161
Outstanding effects on antithrombin activity of modified TBA diastereomers containing an optically pure acyclic nucleotide analogue 155
Nanogravimetric and Optical Characterizations of Thrombin Interaction with a Self-Assembled Thiolated Aptamer 155
Design and Synthesis of a cADPR Mimic as a Novel Tool for Monitoring the Intracellular Ca2+ Concentration 155
Self-Assembly of G-Rich Oligonucleotides Incorporating a 3′-3′ Inversion of Polarity Site: A New Route Towards G-Wire DNA Nanostructures 154
Higher-order G-quadruplex structures and porphyrin ligands: Towards a non-ambiguous relationship 152
Synthesis ofC6-Pyridylpurine Nucleosides by Reaction of NebularineN1-Oxide with Pyridinyl Grignard Reagents 152
Studies toward the Synthesis of Smenamide A, an Antiproliferative Metabolite from Smenospongia aurea: Total Synthesis of ent-Smenamide A and 16-epi-Smenamide A 152
PNA-based graphene oxide/porous silicon hybrid biosensor: towards a label-free optical assay for Brugada Syndrome 152
Porous silicon-based aptasensors: The next generation of label-free devices for health monitoring 150
Solid phase synthesis of DNA-3'-PNA chimeras by using Bhoc/Fmoc PNA monomers 149
Investigating the role of T7 and T12 residues on biological properties of Thrombin Binding Aptamer: enhancement of anticoagulant activity by a single nucleobase modification 149
Quadruplex DNA: structural features and potential applications 149
Pseudomonas anguilliseptica Strain-A1 Degradation of Polycyclic Aromatic Hydrocarbons in Soil Microcosms: Focus on Detoxification Activity and Free Water-Soluble Protein Extracts Kinetics and Efficiency 148
Chemical stability studies of mesoporous oxidized silicon for the synthesis of mixed-sequence oligonucleotides 147
1-Substituted 2’-deoxyinosine analogues 146
Design of tailored DNA G-wire nanostructures by self-assembling of short G-rich oligonucleotides incorporating a 3’-3’ inversion of polarity site 146
Exploitation of a Very Small Peptide Nucleic Acid as a New Inhibitor of miR-509-3p Involved in the Regulation of Cystic Fibrosis Disease-Gene Expression 145
A new solid support for the synthesis of oligonucleotide-tetraphenylporphyrin conjugates 144
Synthesis, self-assembly-behavior and biomolecular recognition properties of thyminyl dipeptides 144
Development of Surface Chemical Strategies for Synthesizing Redox-Responsive Diatomite Nanoparticles as a Green Platform for On-Demand Intracellular Release of an Antisense Peptide Nucleic Acid Anticancer Agent 143
Cost-effective, user-friendly detection and preconcentration of thrombin on a sustainable paper-based electrochemical platform 143
New anti-HIV aptamers based on tetra-end-linked DNA G-quadruplexes: effects of the base sequence and ODN length on anti-HIV activity 141
Solid phase synthesis of a thrombin binding aptamer on macroporous silica for label free optical quantification of thrombin 141
Design, synthesis and biochemical investigation, by in vitro luciferase reporter system, of peptide nucleic acids as new inhibitors of miR-509-3p involved in the regulation of cystic fibrosis disease-gene expression 140
Aminosilane functionalizations of mesoporous oxidized silicon for oligonucleotide synthesis and detection 140
Exploring a peptide nucleic acid-based antisense approach for CD5 targeting in chronic lymphocytic leukemia 140
Synthesis and characterization of tetra-end linked oligonucleotides capable of forming monomolecular G-quadruplex 139
The Anti-Proliferative Effect of L-Carnosine Correlates with a Decreased Expression of Hypoxia Inducible Factor 1 alpha in Human Colon Cancer Cells. 139
Synthesis and label free characterization of a bimolecular PNA homo quadruplex 139
SOLID PHASE SYNTHESIS OF OLIGONUCLEOTIDES TETHERED TO OLIGO-GLUCOSE PHOSPHATE TAILS 138
Synthesis of cyclic N1-pentylinosine phosphate, a new structurally reduced cADPR analogue with calcium-mobilizing activity on PC12 cells 138
Innovation and Perspectives in Solid Phase Synthesis & Combinatorial Libraries 137
Label-free probing of G-quadruplex formation by surface-enhanced raman scattering, DNA structures 137
Investigating the Interactions of Peptide Nucleic Acids with Multicomponent Peptide Hydrogels for the Advancement of Healthcare Technologies 136
New linear precursors of cIDPR derivatives as stable analogs of cADPR: A potent second messenger with Ca2+-Modulating activity isolated from sea urchin eggs 135
Silane Modified Porous Silicon Optical Devices For In Situ Oligonucleotides Synthesis And Detection 134
Synthesis and Evaluation of the Antiproliferative Properties of a Tethered Tubercidin-Platinum(II) Complex 134
cADPR Analogues as Probes for Monitoring the Intracellular Ca2+ concentration 134
Solid phase synthesis of new dinuclear platinum complexes having a modified nucleoside as ligand. 133
Centro di servizio di Ateneo per le Scienze e Tecnologie per la Vita (CESTEV) 133
NUOVE TIPOLOGIE DI G-QUADRUPLEX DI DNA MONOMOLECOLARI 132
New Solid Phase Approach to Obtain 3'-Derivatized Oligonucleotides 132
Targeting cKit87up quadruplex structure with short PNA sequences: a physico-chemical approach 132
Self-Assembly of new G-Rich Oligonucleotides Incorporating a 3’–3’ Inversion of Polarity Site 131
Peptide nucleic acid-mediated circularization of target RNA as tool to inhibit translation 131
Synthesis and Biological Evaluation of a New Structural Simplified Analogue of cADPR, a Calcium-Mobilizing Secondary Messenger Firstly Isolated from Sea Urchin Eggs 131
Probing the DNA reactivity and the anticancer properties of a novel tubercidin-Pt(II) complex 130
6-Chloroxanthosine as useful intermediate for efficient syntheses of [6-15N]-isoguanosine, isoinosine and other purine nucleoside analogues 129
Probing the reactivity of nebularine N1-oxide. A novel approach to C-6 C-substituted purine nucleosides 129
Synthesis and characterization of peptide functionalized nanoparticles for the selective transport across the blood-brain barrier. 129
Carrier capability of halloysite nanotubes for the intracellular delivery of antisense PNA targeting mRNA of neuroglobin gene 128
Introduzione alla chimica organica 127
A Facile Synthesis of 5'-Fluoro-5'-deoxyacadesine (5'-F-AICAR): A Novel Non-phosphorylable AICAR Analogue 127
Fine-Tuning Synthetic Strategies for Decorating Porous Silicon with Carbohydrate Moieties: Towards Enhanced Delivery Systems 126
Synthesis of a new ribose modified analogue of cyclic inosine diphosphate ribose 126
A new ferrocenemethyl-thymidine nucleoside: Synthesis, incorporation into oligonucleotides and optical spectroscopic studies on the resulting single strand, duplex and triplex structures 126
A new synthetic strategy for the prepartion of glyco-peptide conjugates 126
Syntheses of [1-15N]-2'-deoxyinosine, [4-15N]-2'-deoxyAICAR, and [1-15N]-2'-deoxyguanosine. 125
Hydrolysis of oleuropein by recombinant B-glycosidase from hyperthermophilic archaeon Sulfolobus solfataricus immobilised on chitosan matrix 125
Synthesis of mixed-sequence oligonucleotides on mesoporous silicon: chemical strategies and material stability 125
State of art in the chemistry of nucleoside-based Pt(II) complexes 124
Porous Silicon nanoparticles for drug delivery applications 124
Solid phase approach to the preparation of small circular DNA and RNA fragments 124
Silver (I) n‐heterocyclic carbene complexes: A winning and broad spectrum of antimicrobial properties 124
A new solid support for the synthesis of oligonucleotide-tetraphenylporphyrin conjugates 123
B-Amino acid residues: Conformational characterization of an N- and C-protected homo-B-(S)-leucine 123
Design, synthesis and characterization of novel co-polymers decorated with peptides for the selective nanoparticle transport across the cerebral endothelium 123
Synthesis and characterization of a PNA probe targeting the Bcl-2 gene promoter: a promising tool in anticancer treatment 123
Ultrashort Cationic Peptide Fmoc-FFK as Hydrogel Building Block for Potential Biomedical Applications 122
Sinthesis of 1-(2-deoxy-3,5-di-O-acetyl-ß -D-ribofuranosyl)-4-chloro-5- methyl 2(1H) pyrimidinone 122
Exploiting the reactivity of nebularine N1-oxide toward pyridinil Grignard's reagents 122
Use of controlled pore glass in solid phase oligosaccharide synthesis. Application to the semiautomated synthesis of a glyconucleotide conjugate. 121
Nanomeccanismi basati sul DNA e suoi analoghi strutturali coniugato a nanoparticelle magnetiche: progettazione sintesi e controllo. 121
Chimica Organica 121
Higher order G-quadruplex-based aptamers from tetra-end-linkedoligonucleotides with in vitro anti-HIV activity 121
Endogenous and artificial miRNAs explore a rich variety of conformations: a potential relationship between secondary structure and biological functionality 121
CD, UV, and In Silico Insights on the Effect of 1,3-Bis(1′-uracilyl)-2-propanone on Serum Albumin Structure 120
A new solid-phase synthesis of oligonucleotides 3’-conjugated with peptides 120
Direct Synthesis of Oligonucleotides on Nanostructured Silica Multilayers 120
A facile solid phase synthesis of ZMP and of 4-N-alkyl AICAR cyclic diphosphate derivatives 120
Synthesis and preliminary biological evaluation of novel nucleoside-linked platinum complexes 120
A new pattern for helix-turn-helix recognition revealed by PU.1-domain-DNA complex 119
Synthesis of a new N-9 ribityl analogue of cyclic inosine diphosphate ribose (cIDPR) mimic of cyclic ADP ribose (cADPR) 119
cADRP Analogues as Probes for the Cellular Ca2+ Signaling 119
Cytosine-rich oligonucleotides incorporating a non-nucleotide loop: A further step towards the obtainment of physiologically stable i-motif DNA 118
Totale 14.027
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Categoria #
all - tutte 99.983
article - articoli 0
book - libri 0
conference - conferenze 0
curatela - curatele 0
other - altro 0
patent - brevetti 0
selected - selezionate 0
volume - volumi 0
Totale 99.983
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Totale Lug Ago Sett Ott Nov Dic Gen Feb Mar Apr Mag Giu
2021/20221.351 0 1 21 12 8 105 10 56 238 101 281 518
2022/20231.828 276 141 54 196 216 215 18 158 251 169 103 31
2023/20241.097 47 169 162 54 39 65 21 140 19 51 221 109
2024/20257.219 354 372 31 207 183 324 831 491 528 664 2.530 704
2025/202614.218 1.629 1.021 1.432 1.501 2.649 534 1.306 825 1.642 915 326 438
2026/2027426 300 126 0 0 0 0 0 0 0 0 0 0
Totale 30.299