IRIS
VARRA, MICHELA
 Distribuzione geografica
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Continente #
NA - Nord America 1.629
EU - Europa 1.118
AS - Asia 571
AF - Africa 22
OC - Oceania 10
SA - Sud America 6
Continente sconosciuto - Info sul continente non disponibili 1
Totale 3.357
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Nazione #
US - Stati Uniti d'America 1.589
IT - Italia 642
SG - Singapore 292
CN - Cina 185
UA - Ucraina 144
IE - Irlanda 79
FI - Finlandia 71
NL - Olanda 65
DE - Germania 56
CA - Canada 39
VN - Vietnam 34
GB - Regno Unito 22
CI - Costa d'Avorio 21
JP - Giappone 18
SE - Svezia 17
TR - Turchia 11
AU - Australia 10
IN - India 10
HK - Hong Kong 6
CY - Cipro 4
FR - Francia 4
IR - Iran 4
BG - Bulgaria 3
BR - Brasile 3
CH - Svizzera 3
BE - Belgio 2
CL - Cile 2
CZ - Repubblica Ceca 2
ES - Italia 2
GR - Grecia 2
KR - Corea 2
PK - Pakistan 2
RO - Romania 2
AL - Albania 1
BN - Brunei Darussalam 1
CO - Colombia 1
DK - Danimarca 1
EU - Europa 1
IQ - Iraq 1
MA - Marocco 1
PA - Panama 1
TH - Thailandia 1
Totale 3.357
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Città #
Chandler 333
Singapore 244
Napoli 158
Jacksonville 152
Naples 103
Houston 83
Millbury 78
Princeton 70
Woodbridge 70
Amsterdam 63
Nanjing 51
Ashburn 50
Boston 46
Santa Clara 44
Ottawa 38
Beijing 36
Dong Ket 34
Wilmington 29
Rome 21
Des Moines 20
Ann Arbor 16
Jiaxing 14
Hebei 13
Norwalk 13
Nanchang 12
Shenyang 12
Caserta 11
Lawrence 11
Dallas 9
Los Angeles 9
Formia 8
Kronberg 8
Piombino 8
Salerno 8
Tianjin 8
Augusta 7
Casoria 7
Pimpama 7
Barano d'Ischia 6
Boardman 6
Dearborn 6
Indiana 6
Milan 6
Redwood City 6
Changsha 5
Dublin 5
Fairfield 5
Falls Church 5
Messina 5
Mugnano di Napoli 5
Orange 5
Pomigliano D'arco 5
Portici 5
Pune 5
Washington 5
Chengdu 4
Guangzhou 4
Hong Kong 4
Limassol 4
Nishinomiya 4
Seattle 4
Tomiya 4
Belém 3
Capodrise 3
Casalvieri 3
Gold Coast 3
Kunming 3
Marano Di Napoli 3
Mountain View 3
Padula 3
Pavia 3
Teramo 3
Arezzo 2
Ariano Irpino 2
Arzano 2
Athens 2
Brno 2
Casalgrande 2
Central 2
Edinburgh 2
Fisciano 2
Hangzhou 2
Jinan 2
Kapolei 2
La Canada Flintridge 2
Lacco Ameno 2
Leawood 2
Madrid 2
Mortara 2
Munich 2
New York 2
Nocera Superiore 2
Praia A Mare 2
San Diego 2
San Francisco 2
Sant'Antimo 2
Sargodha 2
Torino 2
Torre del Greco 2
Trieste 2
Totale 2.109
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Nome #
Synthesis, structural behaviors and biological properties of thrombin binding aptamers singly modified with chiral m-nitro-benzene glycidoyl moiety 89
Backbone modified TBA analogues endowed with antiproliferative activity 86
Unusual Chair-Like G-Quadruplex Structures: Heterochiral TBA Analogues Containing Inversion of Polarity Sites 75
1-Substituted 2’-deoxyinosine analogues 73
Outstanding effects on antithrombin activity of modified TBA diastereomers containing an optically pure acyclic nucleotide analogue 72
Exploring the photodynamic properties of two antiproliferative benzodiazopyrrole derivatives 71
5-Hydroxymethyl-2′-Deoxyuridine Residues in the Thrombin Binding Aptamer: Investigating Anticoagulant Activity by Making a Tiny Chemical Modification 65
Synthesis of a new ribose modified analogue of cyclic inosine diphosphate ribose 63
Structural studies and biological evaluation of T30695 variants modified with single chiral glycerol-T reveal the importance of LEDGF/p75 for the aptamer anti-HIV-integrase activities 61
6-Chloroxanthosine as useful intermediate for efficient syntheses of [6-15N]-isoguanosine, isoinosine and other purine nucleoside analogues 60
Investigating the role of T7 and T12 residues on biological properties of Thrombin Binding Aptamer: enhancement of anticoagulant activity by a single nucleobase modification 60
Site specific replacements of a single loop nucleoside with a dibenzyl linker may switch the activity of TBA from anticoagulant to antiproliferative 60
Site-specific replacement of the thymine methyl group by fluorine in thrombin binding aptamer significantly improves structural stability and anticoagulant activity 60
Combating Actions of Green 2D-Materials on Gram Positive and Negative Bacteria and Enveloped Viruses 59
A bunch-oligonucleotide forming stable monomolecular quadruplex containing a T-tetrad. 57
Investigating the Role of T7 and T12 Residues on the Biological Properties of Thrombin-Binding Aptamer 57
Introduzione alla chimica organica 56
A facile solid-phase syntesis of oligonucleotides containing a 3’-3’ phosphodiester bond for alternate strand triple-helix formation 55
Synthesis of 3'-3'-linked pyrimidine oligonucleotides containing an acridine moiety for alternate strand triple helix formation 53
Incorporation of a 4-(dimethylamino)azobenzene moiety at 5'-end of TBA and T30695 aptamers: structural characterization of the resulting conjugated G-quadruplexes 53
Synthesis, structural studies and biological properties of new TBA analogues containing an acyclic nucleotide 52
Improved synthesis of isoguanosine and 6-substituted xanthosine derivatives 51
A new synthesis of oxanosine and 2’-deoxyoxanosine 49
New Solid Phase Approach to Obtain 3'-Derivatized Oligonucleotides 49
A bunch-oligonucleotide forming stable monomolecular quadruplex containing a T-tetrad 48
The Effectiveness of Cyrene as a Solvent in Exfoliating 2D TMDs Nanosheets 47
Syntheses of [1-15N]-2'-deoxyinosine, [4-15N]-2'-deoxyAICAR, and [1-15N]-2'-deoxyguanosine. 47
Synthesis of Thymidine Dimers Containing a New Internucleosidic Amide Linkage and their Incorporation into Oligodeoxyribonucleotides 47
Studio 1H-NMR dell’ interazione tra la distamicina A e la netropsina con strutture di duplex e quadruplex DNA 47
Expanding the potential of G-quadruplex structures: formation of a heterochiral TBA analogue 47
Solid phase synthesis of a thrombin binding aptamer on macroporous silica for label free optical quantification of thrombin 47
Synthetic studies on the glycosylation of the base residues of inosine and uridine 46
Photo-control of cancer cell growth by benzodiazoN-substituted pyrrole derivatives 45
Effects of acrolein on the quadruplex forming d(TTAGGG)4 telomeric repeat sequence. 44
A model for triple helix formation on human telomerase reverse transcriptase (hTERT) promoter and stabilization by specific interactions with the water soluble perylene derivative, DAPER. 44
A straightforward modification in the thrombin binding aptamer improving stability, affinity to thrombin and nuclease resistance 44
Synthesis and structural study of quadruplex structures containing 2'-deoxy-8-methyladenosine 43
Synthesis and Characterization of monomolecular DNA G-quadruplex formed by tetra-end-linked oligonucleotides 43
Reaction of 3',5'-di-O-acetyl-2'-deoxyinosine with the chlorinating agent PPh3/CCl4: synthesis of the 6-chloroderivative and of a new base linked dimer, useful intermediate to 15N-1- labelled 2'-deoxyinosine 43
Improved thrombin binding aptamer analogues containing inversion of polarity sites: structural effects of extra-residues at the ends 43
Effect of different solvent condition on cis-trans isomerization of two benzodiazopyrrole derivatives 43
Unusual monomolecular DNA Quadruplex structures using bunch-oligonucleotides 42
Synthesis of 5-methylamino-2'-deoxyuridine derivatives. 41
Spectroscopic properties of two 5′-(4-dimethylamino)azobenzene conjugated G-quadruplex forming oligonucleotides 41
Easy chemical modifications to explore the ‘Janus face’ of TBA: anticoagulant vs antiproliferative properties. 40
Interaction of Distamycin A and Netropsin with Quadruplex and Duplex Structures: a Comparative 1H-NMR study 39
A solid-phase approach to the synthesis of N-1-alkyl analogues of cyclic inosine-diphosphate-ribose (cIDPR) 39
Structural study of four-stranded quadruplex structures containing 2'-deoxy-8-(propyn-1-yl)adenosine 38
Structural and biological studies on new TBA analogues: the role of TBA-quadruplex molecularity in the TBA-thrombin complex 38
Bunchy oligonucleotides forming new stable DNA quadruplex structure 38
Synthesis of triple helix forming oligonucleotides with a phenanthroline moiety into the 3’-3’ inversion site of polarity 37
New Anticancer Agents Mimicking Protein Recognition Motifs. 36
Effect of gamma-hydroxypropano deoxyguanosine, the major acrolein-derived adduct, on monomolecular quadruplex structure of telomeric repeat d(TTAGGG) 4 36
Cis-trans photodynamics of benzodiazopyrrole derivatives in view of biomedical applications 35
Synthesis and characterization of a bunchy oligonucleotide forming a monomolecular parallel quadruplex structure in solution. 35
A new ferrocenemethyl-thymidine nucleoside: Synthesis, incorporation into oligonucleotides and optical spectroscopic studies on the resulting single strand, duplex and triplex structures 35
Easy chemical modifications to explore the ‘Janus face’ of TBA: anticoagulant vs antiproliferative properties. 34
Targeting cKit87up quadruplex structure with short PNA sequences: a physico-chemical approach 32
Synthesis and characterization of DNA quadruplexes containing T-Tetrads formed by bunch-oligonucleotides 31
Toward isolation of palytoxins: Liquid chromatography coupled to low-or high-resolution mass spectrometry for the study on the impact of drying techniques, solvents and materials 31
Synthesis and triple helix formation by alternate strand recognition of oligonucleotides containing 3'-3' phosphodiester bonds 30
Effects of acrolein on the quadruplex forming d(TTAGGG)4 telomeric repeat sequence 29
Solid-phase synthesis of oligonucleotides containing a bipyridine ligand at the 3’-3’ inversion of polarity site. 28
Colleggio dei docenti dottorato di ricerca in Scienze del Farmaco 28
Synthesis of a New N1-Pentyl Analogue of Cyclic Inosine Diphosphate Ribose (cIDPR) as a Stable Potential Mimic of Cyclic ADP Ribose (cADPR) 27
Synthesis of a novel N-1 carbocyclic, N-9 butyl analogue of cyclic ADP ribose (cADPR) 26
Synthesis of a Dibromoperylene Phosphoramidite Building Block and Its Incorporation at the 5' End of a G-Quadruplex Forming Oligonucleotide: Spectroscopic Properties and StructuralStudies of the Resulting Dibromoperylene Conjugate 26
Unusual Monomolecular DNA Quadruplex Structures Using Bunch-Oligonucleotides 24
Synthetic studies on the glycosylation of the base residues of inosine and uridine 23
Synthesis of a new N-9 ribityl analogue of cyclic inosine diphosphate ribose (cIDPR) mimic of cyclic ADP ribose (cADPR) 23
Tetrasubstituted Pyrrole Derivative Mimetics of Protein–Protein Interaction Hot-Spot Residues: A Promising Class of Anticancer Agents Targeting Melanoma Cells 22
Synthesis of N-1-alkyl analogues of cyclic inosine diphosphate ribose (cIDPR) by a new solid phase approach. 22
Sintesi di oligonucleotidi contenenti una unità di fenantrolina nel sito di inversione della polarità 3’-3’. 22
New solid-phase approach to obtain 3’-derivatized oligonucleotides 21
Superstructural self-assembly of the G-quadruplex structure formed by the homopurine strand in a DNA tract of human telomerase gene promoter 21
Synthesis of new ribose modified analogues of cyclic inosine diphosphate ribose (cIDPR) 21
Sintesi di nuovi analoghi dell'ADPRc 20
P21-64 Characterization of the toxic effects by the marine toxin ovatoxin-a on human skin keratinocytes 20
Sintesi di nuovi analoghi dell’IDPR ciclico 19
Dereplication of Gambierdiscus balechii extract by LC-HRMS and in vitro assay: First description of a putative ciguatoxin and confirmation of 44-methylgambierone 18
Synthesis of New Acadesine (AICA-riboside) Analogues Having Acyclic d-Ribityl or 4-Hydroxybutyl Chains in Place of the Ribose 18
Aptamer-Based Biosensors for the Analytical Determination of Bisphenol A in Foodstuffs 17
Targeting G-Quadruplex Structure in the Human c-Kit Promoter with Short PNA Sequences 17
Synthesis of quadruplex-forming tetra-end-linked oligonucleotides: Effects of the linker size on quadruplex topology and stability 16
Solid-phase synthesis of a new diphosphate 5-aminoimidazole-4-carboxamide riboside (AICAR) derivative and studies toward cyclic AICAR diphosphate ribose 16
Oligonucleotides Containing an Acridine Group Covalently Bonded to the Nucleotide Flanking the 3′-3′ Phosphodiester Junction for Alternate Strand Triple Helix Formation 16
SYNTHESIS OF A NEW N-9 RIBITYL ANALOGUE OF CYCLIC INOSINE DIPHOSPHATE RIBOSE (cIDPR) AS A MIMIC OF CYCLIC ADP RIBOSE (cADPR) 15
Synthesis of a new N1-pentyl analogue of cyclic inosine diphosphate ribose (cIDPR) as a stable potential mimic of cyclic ADP ribose (cADPR) 13
Isolation of ovatoxin-a from Ostreopsis cf. ovata cultures. A key step for hazard characterization and risk management of ovatoxins 11
Untargeted LC-HRMS applied to microcystin-producing cyanobacterial cultures for the evaluation of the efficiency of chlorine-based treatments commonly used for water potabilization 10
Totale 3.571
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Categoria #
all - tutte 15.403
article - articoli 0
book - libri 0
conference - conferenze 0
curatela - curatele 0
other - altro 0
patent - brevetti 0
selected - selezionate 0
volume - volumi 0
Totale 15.403
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Totale Lug Ago Sett Ott Nov Dic Gen Feb Mar Apr Mag Giu
2019/2020203 0 0 0 0 47 7 11 17 2 13 53 53
2020/2021483 22 31 24 43 47 50 39 27 67 4 71 58
2021/2022516 3 6 14 3 3 31 0 21 91 59 90 195
2022/2023717 103 78 11 84 70 81 15 57 95 72 36 15
2023/2024440 24 58 53 30 17 32 28 49 15 20 89 25
2024/2025404 110 142 21 50 81 0 0 0 0 0 0 0
Totale 3.571